Gestational diabetes mellitus (GDM) is characterized by glucose intolerance with onset or first recognition during pregnancy. Affecting approximately 7-10% of pregnancies globally, GDM poses significant health risks to both mothers and their infants. Current research has established that GDM is linked to various factors, including hormonal changes during pregnancy and genetic predisposition leading to impaired insulin sensitivity and ß-cell dysfunction. The condition can lead to complications such as preeclampsia, caesarean delivery, and the later development of type 2 diabetes in the mother, as well as macrosomia and neonatal hypoglycemia in the infant. Despite significant advances in understanding the pathophysiology of GDM, there remain critical gaps in effectively diagnosing, treating, and preventing this condition.
The primary goal of this collection is to address the pressing questions and challenges associated with GDM. Key issues include the development of more accurate diagnostic criteria, effective and personalized treatment options including novel technical approaches for glucose monitoring, and strategies for preventing GDM and its associated complications. We aim to explore the endocrinological mechanisms underpinning GDM to improve clinical outcomes. This issue seeks to bring together cutting-edge research and clinical practices to offer a comprehensive overview of current knowledge and future directions. By focusing on the endocrinology aspects, we hope to uncover novel insights into hormone regulation, insulin resistance, and metabolic changes during pregnancy.
The scope of this collection includes but is not limited to the following sub-areas:
• Emerging Biomarkers: Identifying novel biomarkers for early detection and prognosis of GDM.
• Diagnostic Criteria and Screening Methods: Assessing current practices and exploring innovative diagnostic tools.
• Treatment Protocols: Evaluating the effectiveness of dietary management, physical activity, pharmacological treatments.
• Preventive Strategies: Investigating preventive measures pre-pregnancy and during early pregnancy.
• Maternal and Neonatal Outcomes: Studying the short-term and long-term health outcomes for both mothers and their offspring.
• Methodological and Technological Advancements: Utilizing innovative methodology and technology in monitoring and managing GDM (such as Machine Learning, Continuous Glucose Monitoring, etc).
This collection invites researchers, clinicians, and healthcare professionals to contribute original research articles, reviews, and case studies that advance our understanding of gestational diabetes. By addressing these critical areas, we aim to foster a deeper understanding of GDM and improve the health outcomes for affected women and their children.
Gestational diabetes mellitus (GDM) is characterized by glucose intolerance with onset or first recognition during pregnancy. Affecting approximately 7-10% of pregnancies globally, GDM poses significant health risks to both mothers and their infants. Current research has established that GDM is linked to various factors, including hormonal changes during pregnancy and genetic predisposition leading to impaired insulin sensitivity and ß-cell dysfunction. The condition can lead to complications such as preeclampsia, caesarean delivery, and the later development of type 2 diabetes in the mother, as well as macrosomia and neonatal hypoglycemia in the infant. Despite significant advances in understanding the pathophysiology of GDM, there remain critical gaps in effectively diagnosing, treating, and preventing this condition.
The primary goal of this collection is to address the pressing questions and challenges associated with GDM. Key issues include the development of more accurate diagnostic criteria, effective and personalized treatment options including novel technical approaches for glucose monitoring, and strategies for preventing GDM and its associated complications. We aim to explore the endocrinological mechanisms underpinning GDM to improve clinical outcomes. This issue seeks to bring together cutting-edge research and clinical practices to offer a comprehensive overview of current knowledge and future directions. By focusing on the endocrinology aspects, we hope to uncover novel insights into hormone regulation, insulin resistance, and metabolic changes during pregnancy.
The scope of this collection includes but is not limited to the following sub-areas:
• Emerging Biomarkers: Identifying novel biomarkers for early detection and prognosis of GDM.
• Diagnostic Criteria and Screening Methods: Assessing current practices and exploring innovative diagnostic tools.
• Treatment Protocols: Evaluating the effectiveness of dietary management, physical activity, pharmacological treatments.
• Preventive Strategies: Investigating preventive measures pre-pregnancy and during early pregnancy.
• Maternal and Neonatal Outcomes: Studying the short-term and long-term health outcomes for both mothers and their offspring.
• Methodological and Technological Advancements: Utilizing innovative methodology and technology in monitoring and managing GDM (such as Machine Learning, Continuous Glucose Monitoring, etc).
This collection invites researchers, clinicians, and healthcare professionals to contribute original research articles, reviews, and case studies that advance our understanding of gestational diabetes. By addressing these critical areas, we aim to foster a deeper understanding of GDM and improve the health outcomes for affected women and their children.