About this Research Topic
Severe eosinophilic disorders present a significant clinical challenge. This is due to several factors, including the varied etiologies, a high tendency to recur, and a frequent need to treat with long-term systemic steroids, accompanied by a host of short- and long-term side effects. Eosinophilic disorders can in certain circumstances be life threatening. Lessons from the recent emergence of anti-IL-5 monoclonal antibody therapies have highlighted the clinical benefits of eosinophil depletion.
To promote improved understanding of the eosinophil, a pleiotropic multifunctional leukocyte, and associated eosinophilic diseases, potentially leading to advances in clinical management, we seek articles from basic science to clinical investigations that cover, but are not limited to:
1. Physiological roles of eosinophils.
2. Immuno-regulatory properties of eosinophils.
3. Eosinophilic lung diseases (e.g. allergic bronchopulmonary aspergillosis/mycosis, eosinophilic asthma, aspirin-induced asthma, eosinophilic pneumonias).
4. Eosinophilic gastrointestinal diseases.
5. Eosinophilic granulomatosis with polyangitis (EGPA).
6. Eosinophilic otological diseases (e.g. allergic fungal sinusitis, eosinophilic otitis media, chronic rhinosinusitis with nasal polyps, eosinophilic chronic rhinosinusitis).
7. Eosinophilic skin and subcutaneous diseases.
8. Eosinophilic heart diseases.
9. Hypereosinophilic syndromes.
10. Eosinophilic parasitic diseases.
We welcome the submission of Original Research, Review and Opinion articles, Methods, and Case reports which address relevant insights into the field in this Research Topic. Basic studies on eosinophils and eosinophil physiology may also be included.
Keywords: Eosinophils, Eosinophilic disorders
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.