Research Topic

Biomarker Exploration in Neuropsychiatry: Understanding of the Pathophysiology and Therapeutic Implications

About this Research Topic

Biomarkers are increasingly sought to detect early onset of illness, to enhance diagnostic certainty, provide prognostic criteria, and permit the mapping of therapeutic outcome in a variety of disorders. Although biomarker science is a field that is advancing rapidly in medicine as a whole, neuropsychiatric disorders are long suffering from an absence of adequate biomarkers and laboratory tests. Despite increasing efforts, the causes of many neuropsychiatric disorders remain unclear. Moreover, it is difficult to provide diagnostic criteria or to assess the therapeutic outcome using the current standard of behavior rating scores. During the past two decades of “omic” era, inspiring advances in genomic, transcriptomic, proteomic and metabolomic knowledge and technologies have provided us with new avenues to investigate biomarkers in neuropsychiatric disorders. In addition, rapid developments in bioinformatics and neuroimaging techniques are aiming to fill the gaps in knowledge among different omic platforms. This Research Topic will thus focus on how the identified biomarkers utilizing the state-of-art technologies reveal the genetic, neuroendocrinologic, neuropharmacologic and psychosomatic mechanisms underlying the neuropsychiatric disorders and their implications for prevention and treatment strategies.


Keywords: Genomics, Proteomics, Metabolomics, Biomarkers, Psychiatry


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Biomarkers are increasingly sought to detect early onset of illness, to enhance diagnostic certainty, provide prognostic criteria, and permit the mapping of therapeutic outcome in a variety of disorders. Although biomarker science is a field that is advancing rapidly in medicine as a whole, neuropsychiatric disorders are long suffering from an absence of adequate biomarkers and laboratory tests. Despite increasing efforts, the causes of many neuropsychiatric disorders remain unclear. Moreover, it is difficult to provide diagnostic criteria or to assess the therapeutic outcome using the current standard of behavior rating scores. During the past two decades of “omic” era, inspiring advances in genomic, transcriptomic, proteomic and metabolomic knowledge and technologies have provided us with new avenues to investigate biomarkers in neuropsychiatric disorders. In addition, rapid developments in bioinformatics and neuroimaging techniques are aiming to fill the gaps in knowledge among different omic platforms. This Research Topic will thus focus on how the identified biomarkers utilizing the state-of-art technologies reveal the genetic, neuroendocrinologic, neuropharmacologic and psychosomatic mechanisms underlying the neuropsychiatric disorders and their implications for prevention and treatment strategies.


Keywords: Genomics, Proteomics, Metabolomics, Biomarkers, Psychiatry


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

01 March 2018 Abstract
01 December 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

01 March 2018 Abstract
01 December 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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