The Pupil: Behavior, Anatomy, Physiology and Clinical Biomarkers

262.9K

views

102

authors

25

articles

The Pupil: Behavior, Anatomy, Physiology and Clinical Biomarkers

262.9K

views

102

authors

25

articles

Editorial

09 April 2020

Editorial: The Pupil: Behavior, Anatomy, Physiology and Clinical Biomarkers

Andrew J. Zele

and

Paul D. Gamlin

7,115 views

24 citations

Editors

2

Queensland University of Technology

University of Alabama at Birmingham

Impact

Fetching...

About

The pupil response is more than a simple light evoked reflex. At any moment, the pupil diameter reflects the activity of complex neurological pathways to changes in the environmental illumination and autonomic activity through parasympathetic and sympathetic innervations. A mobile pupil also modulates retinal illumination and enhances visual performance by affecting depth of focus and optical aberrations. This Research Topic will therefore highlight the latest research on external and internal influences on pupillary responses in humans and animal models. Studies of afferent pathways can include investigations of classical (rod and cone) photoreceptors and the melanopsin expressing intrinsically photosensitive retinal ganglion cells (ipRGC). There will be an emphasis on the non-invasive measurement of the pupil as a clinically significant neurological marker of autonomic, midbrain and central brain function and on discoveries presented by leading experts at the 32nd international Pupil Colloquium in Switzerland. Consequently, this Research Topic will bring together in one place the latest understanding of the afferent and efferent pupil control pathways, pharmacological effects on pupil function and the influence of non-photic control factors, including cognition and attention, sleepiness and circadian processing.

The pupil response is more than a simple light evoked reflex. At any moment, the pupil diameter reflects the activity of complex neurological pathways to changes in the environmental illumination and autonomic activity through parasympathetic and sympathetic innervations. A mobile pupil also modulates retinal illumination and enhances visual performance by affecting depth of focus and optical aberrations. This Research Topic will therefore highlight the latest research on external and internal influences on pupillary responses in humans and animal models. Studies of afferent pathways can include investigations of classical (rod and cone) photoreceptors and the melanopsin expressing intrinsically photosensitive retinal ganglion cells (ipRGC). There will be an emphasis on the non-invasive measurement of the pupil as a clinically significant neurological marker of autonomic, midbrain and central brain function and on discoveries presented by leading experts at the 32nd international Pupil Colloquium in Switzerland. Consequently, this Research Topic will bring together in one place the latest understanding of the afferent and efferent pupil control pathways, pharmacological effects on pupil function and the influence of non-photic control factors, including cognition and attention, sleepiness and circadian processing.

Download ebook

Share

Editors

Queensland University of Technology

University of Alabama at Birmingham

Impact

262,872 Total views

211,662 Article views

47,235 Article downloads

3,975 Topic views

Published In

Journal Thumbnail

Frontiers in Neurology

Neuro-Ophthalmology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic