About this Research Topic
Stem Cells investigation in Endocrinology, leading stem cell scientists and developmental endocrinologists, critically review both cutting-edge approaches to stem cell biology and the application of stem cells to endocrine diseases, including diabetes, tissue/organ repairs, energy metabolism and metabolic disorders.
Current research trends in Endocrinology are direct to modify stem cells, develop an endocrine-like cell, and use adult mesenchymal stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases.
Several growth factor ligand and receptor gene products have been shown to play roles during wound healing in endocrine-related diseases such as foot ulcers that affect a range of patients with diabetes, resulting in a great health burden.
During recent years, along with advances in the biomedical sciences, various surgical and non-surgical therapeutic methods have been suggested to promote wound healing, and growth factors involved in these processes are currently widely investigated, including epidermal growth factor, vascular endothelial growth factor, transforming growth factor-beta, fibroblast growth factor, platelet concentrates and erythropoietin, which could facilitate wound healing of patients with diabetes.
The aim of this Research Topic is to bring an update on the latest evidence regarding the use of stem cells and growth factors in Endocrinology.
Overviews, reviews, and original papers regarding the following sub-topics and other similar studies are warmly welcome:
• The innovative aspects of stem cells and growth factors biology;
• Their secretome, within the context of isolation, derivation, reprogramming, self-renewal, quality control,
feasibility, “proof-of-concept” studies;
• New methodological paradigms that challenge current thinking in clinical research, differentiation, transplantation;
• New sources of stem cells;
• Approaches promoting endocrine development from stem cells; and
• Evidence for endocrine cell function from stem cells.
Keywords: Stem cells research and therapy, Translational endocrinology, Cell biology, Growth factors, Diseases