Vascular Function and Aging: a Focus on Oxidative Stress

This Research Topic is part of the series on Vascular Function and Aging. Other titles in this series are:

• Vascular Function and Aging: Hypertension, Obesity and Metabolic Disorders

• Vascular Function and Aging: Mechanisms of Aging and Vascular Integrity

• Vascular Function and Aging: Molecular And Omics Approaches To Study Aging Vasculature

As we age, the vasculature in our body goes toward morphological, structural and functional changes, even in healthy individuals.

These mechanisms are at the basis of many cardiovascular and age-related diseases.

Among the many changes happening during aging, vascular cells experience a change in their redox homeostasis. An enhanced oxidative stress in the vasculature causes a wide range of alterations.

This Research Topic welcomes basic, translational, computational, and applied research on the redox state and alterations in the vasculature during aging. Potential areas of interest may include, but are not limited to:

- vascular health: redox homeostasis, maintaining a healthy vasculature;

- redox homeostasis: a link between inflammation and vascular aging;

- ischemic heart disease: oxidative stress caused by this condition and the consequences on the individual;

- nutritional strategies to prevent cardiovascular diseases: antioxidants in nutrition to reduce oxidative stress and prevent disease onset;

- healthy aging and vascular rehabilitation in the elder population, focusing on reducing systemic stress.

We welcome submissions of different article types to this collection, especially reviews, mini-reviews, and original research papers.

Even though abstract submission is not mandatory, we encourage all interested researchers to submit an abstract before submitting their manuscript. Abstracts do not have to coincide with the final abstract of the manuscripts.

Keywords: Aging, vascular function, oxidative stress, redox imbalance, antioxidants, endothelial dysfunction, vascular aging, redox signaling

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.