About this Research Topic
Gaining insight into the cellular activities controlled by chemokine receptors in leukocytes as well as the signaling pathways driving these functions can be useful to develop strategies to modulate the immune response.
In this Research Topic, we aim to discuss the range of functions orchestrated by chemokine receptors and other non-chemokine chemoattractant receptors of leukocytes, beyond chemotaxis, including their roles in:
(i) Immune cell metabolism.
(ii) Immune cell differentiation.
(iii) Immune cell polarization.
(iv) Immune cell survival.
In this way, we aim to uncover novel targets and signaling pathways that could be exploited for modulating immune responses under normal conditions and in disease.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.