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Scope
The release of soluble mediators represents one of main cell-to-cell communication strategies. Soluble mediators include a broad variety of molecules, such as proteins, eicosanoids, pattern recognition receptors, antimicrobial peptides, microRNAs, nucleosides and exosomes. This section welcomes studies on the relevance of this major cell-to-cell communication strategy in the regulation of immune responses, both in preclinical models and the human setting.
Scope
The release of soluble mediators represents one of main cell-to-cell communication strategies. Soluble mediators include a broad variety of molecules, such as proteins, eicosanoids, pattern recognition receptors, antimicrobial peptides, microRNAs, nucleosides and exosomes. This section welcomes studies on the relevance of this major cell-to-cell communication strategy in the regulation of immune responses, both in preclinical models and the human setting. The topics that will be covered include:
- the role of chemotactic factors in the homing and activation of leukocyte subsets;
- the role of lipid mediators in the onset and resolution of inflammation;
- the role of innate immune proteins, such as soluble pattern recognition receptors and antimicrobial peptides in protective and autoreactive immune responses;
- the role of purinergic receptors in the regulation of innate and adaptive immunity;
- the role of circulating exosomes and miRNAs in pathological immune reactions.
Indexed in: PubMed, PubMed Central, Scopus, Web of Science, Google Scholar, DOAJ, CrossRef, Chemical Abstracts Service (CAS), EMBASE, Semantic Scholar, Ulrich's Periodicals Directory, CLOCKSS, EBSCO, OpenAIRE, Zetoc
PMCID: all published articles receive a PMCID
Cytokines and Soluble Mediators in Immunity welcomes submissions of the following article types: Case Report, Classification, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Systematic Review and Technology and Code.
All manuscripts must be submitted directly to the section Cytokines and Soluble Mediators in Immunity, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Cytokines and Soluble Mediators in Immunity will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Immunology.
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