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MINI REVIEW article

Front. Immunol.

Sec. Cytokines and Soluble Mediators in Immunity

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1655560

This article is part of the Research TopicAdvancing Immune Research in Chronic Liver Diseases Through New Approach MethodologiesView all articles

Mini-review: Serum immunoglobulins and MASLD

Provisionally accepted
Ke Qian  ChenKe Qian Chen1*Wen-Jing  CaoWen-Jing Cao1Shu-Zhi  WangShu-Zhi Wang2Wei  LiWei Li1
  • 1Xiangtan Central Hospital, Xiangtan, China
  • 2University of South China, Hengyang, China

The final, formatted version of the article will be published soon.

With the development of society and the economy, metabolic dysfunction-associated steatotic liver disease (MASLD) has become a major chronic disease in contemporary society. Finding a safe, effective, and economical diagnostic method is essential for the prevention of MASLD. Serum immunoglobulin is a protein produced by the B cells after the body is stimulated by an external antigen or pathogen. It is very interesting and valuable to explore the relationship between serum immunoglobulins and MASLD. Unfortunately, only a small number of studies have explored the relationship between serum immunoglobulins and MASLD. Therefore, we review the research progress of serum immunoglobulins in MASLD. At the same time, we also discuss the shortcomings of these studies. We hope this review will provide experience and reference for the prevention of MASLD in the future.

Keywords: Serum immunoglobulins, serum biomarker, MASLD, NASH, Fibrosis

Received: 28 Jun 2025; Accepted: 28 Jul 2025.

Copyright: © 2025 Chen, Cao, Wang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ke Qian Chen, Xiangtan Central Hospital, Xiangtan, China

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