Among the world's top 10 most-cited Immunology journals
Inflammation plays a fundamental role in nearly all chronic degenerative diseases and the contribution of pro-inflammatory cytokines in neurodegenerative, cardiovascular and bone diseases has become a major area of investigation. Lessons from cytokine biology are at the core of understanding inflammation. Blocking a cytokine with a “biological” outside the cell continues to be highly effective in treating several diseases and without organ toxicity. Several post-receptor signaling kinases are located downstream from cytokine-activated cells, which have become new targets to tame inflammation. Orally active small molecule inhibitors of intracellular signaling kinases will likely be the new frontier of anti-inflammatory agents.
The scope of the section Inflammation will be broad and include clinically relevant areas of investigation which apply to the following areas:
- Pro-inflammatory cytokines;
- The effects of innate inflammation;
- How inflammation affects the immune system;
- Cell signaling during inflammation.
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PMCID: all published articles receive a PMCID
Inflammation welcomes submissions of the following article types: Case Report, Classification, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Protocols, Review, Systematic Review and Technology Report.
All manuscripts must be submitted directly to the section Inflammation, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Inflammation will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Immunology.