Frontiers in Immunology

Review

Accepted on 12 Sep 2025

Gene expression silencing therapy in tumors, focus on gastrointestinal and genitourinary tumors

in Cancer Immunity and Immunotherapy

Nathan El-Ghazzi
Eurydice Angeli

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657040

3,556 views

Original Research

Accepted on 12 Sep 2025

Real-world disproportionality analysis of cardiac failure associated with novel antineoplastic agents in breast cancer: a pharmacovigilance study

in Cancer Immunity and Immunotherapy

Hui Li
Yingjia Wu
Qin Guo
Chengshan Guo
FangJie Liu
Lanqing Huo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680909

3,523 views

Review

Accepted on 12 Sep 2025

Notch Signalling in T cells: Bridging Tumour Immunity and Intratumoral Cellular Crosstalk

in Cancer Immunity and Immunotherapy

Jasmine Sultana
Pritha Roy Choudhury
Saurav Bera
Mohona Chakravarti
Aishwarya Guha
Prodipto Das
Juhina Das
Gayatri S Iyer
Anirban Sarkar
Sukanya Dhar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659614

370 views

Original Research

Accepted on 12 Sep 2025

A High-Calorie Diet Exacerbates Lipopolysaccharide-Induced Pneumonia by Promoting Acetate-Mediated Macrophage Polarization via the HDAC9/10–HIF-1α–Glycolysis Axis

in Inflammation

Qianqian Li
Hui Liu
Chen Bai
Lin Jiang
Chen Su
Xueying Qin
Tiegang Liu
Xiaohong Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614768

338 views

Original Research

Accepted on 12 Sep 2025

Essential roles of CTCF binding sites at TAD boundaries in modulating chromatin interactions and transcriptional regulation at the Ifng locus

in T Cell Biology

Kazuya Muto
Daiki Yoshida
Toshiyuki Suzuki
Natsuo Yamamoto
Naokazu Inoue
Akiko Murakami-Sekimata
Ken Iseki
Masayuki Sekimata

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667851

274 views

Original Research

Accepted on 12 Sep 2025

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Jiezhong Deng
Jun Gu
Xiaoshan Gong
Hao Tang
Yuyi Cai
Yusheng Yang
Shi-Wu Dong
Chunrong Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630253

296 views

Original Research

Accepted on 12 Sep 2025

Integrated transcriptomic and single-cell RNA-seq analysis identifies CLCNKB, KLK1 and PLEKHA4 as key gene of AKI-to-CKD progression

in Systems Immunology

Fanhua Zeng
Zhenhua Yang
Zufeng Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628962

288 views

Original Research

Accepted on 12 Sep 2025

Deep learning-aided inter-species-comparison reveals shared and distinct molecular patterns in cynomolgus monkey and humans following non-specific T cell activation

in Systems Immunology

Vincent D Friedrich
Kari Neier
Kristina Müller
Birgit Fogal
Zuzana Loncova
Michael Rade
Muhammad Shoaib
Ulrike Köhl
Kathleen Hoyt
Parimal Pande

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603716

289 views

Case Report

Accepted on 12 Sep 2025

Mevalonate kinase deficiency: an underdiagnosed cause of ischemic stroke – characterization of a novel genetic variant

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Lyna-Nour Hamidi
Jack Christopher Drda
Meriem Belhocine
Hannah-Laure Elfassy
Stéphanie Ducharme-Bénard
Maxime Chayer-Lanthier
Bushra Sultana
Sylvain Lanthier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651819

268 views

Original Research

Accepted on 12 Sep 2025

Progenitor-Exhausted T Cell as Prognostic Indicator in Esophageal Squamous Cell Carcinoma: Illuminating Their Key Contribution to Tumor Immunity

in Cancer Immunity and Immunotherapy

Yi Liu
Hongwei Jiang
Fang Zhang
Bin Xu
Junjun Chen
Xiao Zheng
Renhao Geng
Lujun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659077

307 views

Original Research

Accepted on 12 Sep 2025

Scalp Seborrheic Dermatitis Demonstrates a Skewing of Th1 Activation: A Proteomic Study in Lesional Skin

in Inflammation

Ningning Shen
Wei Chen
Lihua Hu
Jia Huang
Qiang Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638710

294 views

Original Research

Accepted on 12 Sep 2025

Targeting Caspase-1 in Osteoarthritis: Multi-Omics Insights into the Effects of VX-765 on Human Chondrocyte Function and Phenotype

in Inflammation

Jian Mei
Nicole Schäfer
Penghui Wei
Zhiheng Kong
Shushan Li
Patrick Pann
Marianne Ehrnsperger
Brian Johnstone
Eva Matalova
Susanne Grässel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677801

336 views

Original Research

Published on 12 Sep 2025

The germinal center-tertiary lymphoid structure after neoadjuvant chemo-immunotherapy for locally advanced lung squamous cell carcinoma can predict the disease progression

in Cancer Immunity and Immunotherapy

Lili Jiang
Shuang Li
Ping Zhou
Yan Huang
Min Chen
Chan Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579840

425 views

Case Report

Published on 12 Sep 2025

Long-term survival benefit from third-line treatment for advanced colon cancer: a case report

in Cancer Immunity and Immunotherapy

Ju Su
Yuqing Kuang
Yiwen Wu
Qun Chen
Shadong Min

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639287

282 views

General Commentary

Published on 12 Sep 2025

Commentary: Long COVID in pediatric age: an observational, prospective, longitudinal, multicenter study in Italy

in Viral Immunology

Cristiana Indolfi
Angela Klain
Giulio Dinardo
Carolina Grella
Maria Maddalena Marrapodi
Michele Miraglia del Giudice

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624011

171 views

Original Research

Published on 12 Sep 2025

Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages

in Cancer Immunity and Immunotherapy

Ik-Hwan Han
Ilseob Choi
Soyoung Kim
Minjin Kwon
Hyojung Choi
Hyunsu Bae

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652166

435 views