Frontiers in Immunology

Original Research

Published on 30 Sep 2025

FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

in Inflammation

Zhongchen Li
Tengkun Yin
Hongyang Guo
Zhenxing Liu
Peijian Wang
Chao Liu
Qingbo Wang
Meng Zhang
Yilei Xiao
Jiyue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609989

194 views

Original Research

Accepted on 29 Sep 2025

The inflammatory architecture reflects the effects of pharmacological and genetic interventions on resolution of TLR2-mediated inflammation

in Inflammation

Clara Kramer
Sandra Pierre
Nicole Zander
Anja Kolbinger
Blerina Aliraj
Andreas Weigert
Klaus Scholich

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633348

Mini Review

Accepted on 29 Sep 2025

Functional Heterogeneity of Mast Cells in Cutaneous Inflammation: Implications for Precision Medicine

in Inflammation

Surui A
Dugarmaa Ulzii
Enkhtur Yadamsuren
Jihai Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680574

Original Research

Accepted on 29 Sep 2025

Integrating Bioinformatics and Molecular Experiments to Reveal the Critical Role of the Cellular Energy Metabolism-Related Marker PLA2G1B in COPD Epithelial Cells

in Inflammation

Jun Shi
Zihan Wang
Yafei Rao
Dan-Yang Li
Ying Luo
Yue Zhang
Yuqiang Pei
Xiaoyan Gai
Yongchang Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666195

Review

Accepted on 29 Sep 2025

THERAPEUTIC CHALLENGES IN CENTRAL NERVOUS SYSTEM VIRAL INFECTIONS: ADVANCING MESENCHYMAL STEM CELL-BASED STRATEGIES FOR TREATING NEUROINFLAMMATION AND PROMOTING TISSUE REPAIR

in Inflammation

Javier Carbone-Schellman
Javiera Fontecilla-Escobar
Nicolás Sales-Salinas
William Chaparro
Alfredo Enrique Molina-Berríos
María Celeste Ruete
Pablo A. González
Mayra A. Machuca
Ma. Cecilia Opazo
Marcelo Ezquer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677433

Brief Research Report

Accepted on 29 Sep 2025

Sulphur compounds navigate redox processes, leukotriene synthesis and ω-hydroxylation of leukotriene B4 at neutrophil interaction with bacteria Salmonella typhimurium: the way to manipulate neutrophil swarming

in Inflammation

Ekaterina Golenkina
Sofia V. Navarnova
Galina M. Viryasova
Svetlana Galkina
Tatjana V. Gaponova
Yulia M. Romanova
Galina F. Sud’ina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606408

Original Research

Accepted on 29 Sep 2025

ATF3 prevents retinal ganglion cell apoptosis and mitigates microglia-mediated neuroinflammation in retinal ischemia–reperfusion injury

in Inflammation

Ningzhi Zhang
Tian Tian
Zhiyi Wang
Xuejun He
Wenye Cao
Wenxi Zhang
Yiqiao Xing
Ning Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671204

Review

Accepted on 29 Sep 2025

Fatty Acid Metabolism in Gouty Arthritis: Mechanisms to Therapeutic Targeting

in Inflammation

Xueping Zhao
Ye Sun
Le Yang
Hui Sun
Xinya Zhang
Hui Sun
Guangli Yan
Xijun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671548

Original Research

Accepted on 29 Sep 2025

LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis

in Inflammation

Renshengjie Zhao
Lan Wang
Yang Zhou
Keming Xiao
Qiqi Liu
Ke Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650984

Review

Accepted on 29 Sep 2025

Peripheral immune and metabolic regulation of Aβ and Tau by exercise in Alzheimer's disease

in Inflammation

Yuehan Yu
Kang Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678526

Original Research

Accepted on 29 Sep 2025

Multi-omics Analysis and Evidence of IL1R1 as a Potential Biomarker for Diabetes-associated Intervertebral Disc Degeneration

in Inflammation

Meng Yi
Peichuan Xu
Wancheng Lin
Shijie Liu
Jipeng Song
Yukun Yin
Lixiang Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692185

Brief Research Report

Accepted on 29 Sep 2025

Low-dose emapalumab treatment in refractory macrophage activation syndrome secondary to adult onset still’s disease/systemic lupus erythematosus: insights from nine cases

in Inflammation

Jie Chen
Liling Zhao
Yanwei Lin
Xinyue Lian
Haiting Wang
Liyang Gu
Ran Wang
Xiaodong Wang
Shuang Ye
QIong Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676749

Original Research

Accepted on 29 Sep 2025

Mast cells are essential in the development of exposure-associated exercise-induced bronchoconstriction in a mouse model

in Inflammation

Nora Fopke Marain
Fien Byttebier
Marieke Colemont
Ellen Dilissen
Jonathan Cremer
Dominique MA Bullens
Lieven J. Dupont
Jeroen A. Vanoirbeek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650057

Review

Accepted on 29 Sep 2025

Liposome-Mediated Macrophage Reprogramming: Emerging Strategies for Chronic Disease Therapy

in Inflammation

hongnv zhang
Nan Hu
Zhenghao Wang
Shaodong Zhai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653642

Original Research

Published on 29 Sep 2025

Analysis of GSDMD-N abnormality promoting neutrophil NETs mediated RA disease through NLRP3-dependent pathway

in Inflammation

Yali Sang
Huiyang Liu
Bingle Li
Lingyan Zhu
Yongfu Wang
Li Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652608

1,349 views

Original Research

Published on 29 Sep 2025

Scalp seborrheic dermatitis demonstrates a skewing of Th1 activation: a proteomic study in lesional skin

in Inflammation

Ningning Shen
Wei Chen
Lihua Hu
Jia Huang
Qiang Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638710

841 views