Frontiers in Immunology

Original Research

Published on 18 Feb 2026

Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery

in Inflammation

Xiaoqi Gong
Jiaojiao Feng
Zhe Xu
Yunxiao Xie
Yibo Han
Jing Li
Guodong Tang
Yuxi Liu
Xiaoyun Dong
Shuhan Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1730619

230 views

Review

Published on 18 Feb 2026

Stem cell-based therapies for silicosis: mechanisms, sources, clinical translation, and emerging strategies

in Inflammation

Xinru Feng
Bo Xiao
Lixia Hou
Bingxi Zhang
Lincha Tian
Biwen Mo
Dong Yao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1745174

256 views

Original Research

Published on 18 Feb 2026

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

in Inflammation

Yuming Liu
Yayue Hu
Se-rigeleng
Zhongyi Yang
Xueze Liu
Jiayang Yu
Huihui Li
Songtao Gu
Weitao Yang
Cheng Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1771007

317 views

Review

Published on 18 Feb 2026

Therapies for bronchiectasis: mechanisms and potential effects

in Inflammation

Long Yu
Hong-rui Zhu
Xue-hang Jin
Jin Ding
Ting Jin

Frontiers in Immunology

doi 10.3389/fimmu.2026.1735598

145 views

Original Research

Published on 18 Feb 2026

Identification of immune-mediated aging genes associated with cervical spondylosis through single-cell eQTL Mendelian randomization

in Inflammation

Zuozhong Liu
Haitao Xu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1766215

181 views

Original Research

Published on 18 Feb 2026

Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure

in Inflammation

Xiaoqin Liu
Xuhua Jiang
Xueyun Zhang
Qiankun Hu
Xueping Yu
Jian Sun
Mingqin Lu
Jiming Zhang
Yuxian Huang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1694659

213 views

Original Research

Published on 18 Feb 2026

Dysregulated hyaluronan metabolism drives inflammation and angiogenesis in proliferative diabetic retinopathy

in Inflammation

Ahmed M. Abu El-Asrar
Mohd I. Nawaz
Ajmal Ahmad
Mairaj Siddiquei
Eef Allegaert
Priscilla W. Gikandi
Gert De Hertogh
Ghislain Opdenakker

Frontiers in Immunology

doi 10.3389/fimmu.2026.1724199

252 views

Original Research

Published on 18 Feb 2026

Integrated transcriptomic and functional analyses reveal that NOX2 inhibition rewires the inflammatory landscape of macrophages

in Inflammation

Iswarya Muthukumarasamy
Sharleen M. Buel
Jennifer M. Hurley
Jonathan S. Dordick

Frontiers in Immunology

doi 10.3389/fimmu.2026.1731888

Review

Published on 18 Feb 2026

The role of IL-11 in chronic diseases

in Inflammation

Jingxuan Zhang
Yan Leng
Wenyuan Li
Bihan Wang
Baichuan Yang
Wei Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763360

114 views

Original Research

Published on 18 Feb 2026

Identification of FTO as a key m6A demethylase linking immune dysregulation to sepsis pathogenesis

in Inflammation

Yi Jiao
Rui Lian
Weijian Zhang
Nan Gao
Qishun Geng
Tiantian Deng
Zhaoran Wang
Tingting Deng
Cheng Xiao
Guoqiang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1756059

Original Research

Published on 18 Feb 2026

A multi-machine learning framework identifies novel PANoptosis-related biomarkers and their immune landscape in ulcerative colitis: Insights from transcriptomics and experimental validation

in Inflammation

Yuan Zhao
Xiangjie Zhai
Han Wang
Sen Wang
Siliu Xu
Ni Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1729942

150 views

Original Research

Accepted on 17 Feb 2026

Identification of gemilukast as a bifunctional molecule with lipid-lowering and anti-inflammatory activities

in Inflammation

Yuanyuan Liu
Yixiao Wang
Rufei Wang
Qingshan Yang
Guojun Pan
Renshuai Zhang

Frontiers in Immunology

Editorial

Accepted on 17 Feb 2026

Editorial: Lipids in Immunometabolism

in Inflammation

Francesco Nicoli
Anshu Agrawal
Fabrizia Bonacina
Gareth S. D. Purvis

Frontiers in Immunology

Original Research

Accepted on 17 Feb 2026

Neonatal Pulmonary Vascular Remodeling Induced by Increased Blood Flow Is Associated with an Antiviral-like Immune Signature

in Inflammation

Sixie Zheng
Hao Li
She Siqi
依婷薛
Debao Li
Jiapei Wang
Yuqing Hu
Jing Wang
Lincai Ye

Frontiers in Immunology

Review

Accepted on 17 Feb 2026

Macrophage Plasticity in Thyroid Eye Disease: Dual Effects of Inflammation and Fibrosis

in Inflammation

Xinyu Li
Zhangjun Ren
Lanlan Gao
Chao Xiong
Hongfei Liao

Frontiers in Immunology

Review

Accepted on 17 Feb 2026

Unveiling the Immune Microenvironment in Diabetic Nephropathy: From Mechanisms to Therapeutics

in Inflammation

Tao Jiang
Ran Chen
Jianying Chang
jiajia Duan
Yanqiu Wang
Yuhan Sun
Xiaowan Chen
Yujin Ma
Liwen Zhang
Hongwei Jiang

Frontiers in Immunology

Original Research

Accepted on 17 Feb 2026

Aquaporin-4 Suppresses Neuronal Pyroptosis after Ischemic Stroke via the IκBα/NF-κB Signaling Pathway

in Inflammation

Heling Chu
Jingwei Pan
Qihao Guo
Chuyi Huang

Frontiers in Immunology

Original Research

Accepted on 17 Feb 2026

A Conserved Monocyte Activation Program Links Brain Injury to Systemic Immune Adaptation and Clinical Outcomes

in Inflammation

Abderrahmane Sadek
Melanie Petrier
Cynthia Fourgeux
Martin Braud
Victor Gourain
Marwan Bouras
Cecile Poulain
Mohieddine Moumni
Antoine Roquilly
Jeremie Poschmann

Frontiers in Immunology

Original Research

Accepted on 17 Feb 2026

CCS-Mediated Mechanistic Link Between Gestational Diabetes Mellitus and Carpal Tunnel Syndrome: A Multi-Omic MR Framework

in Inflammation

Rui Chen
Yu Zhang
Xiangbo Meng
Xingyu Ren
Teng Lv
Yihua Sun
Tao Chen

Frontiers in Immunology

Original Research

Published on 17 Feb 2026

Gomphus floccosus (Schw.) Sing. extract attenuates alcoholic liver disease by suppressing macrophage glycolysis and M1 polarization

in Inflammation

Tianyin Ruan
Xutao Li
Mingyue Li
Siyuan Wang
Li Shen
Chenghai Liu
Yuan Peng
Yanyan Tao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1772592

127 views

Original Research

Published on 17 Feb 2026

Amplifying radiation-induced anti-tumor immunity: the dual role of brachytherapy and low-dose total body irradiation

in Inflammation

YingQi Gu
Yang Yang
Jian Gao
ZhouXue Wu
Jia Wang
Chen Xie
XinYi Wang
Min Wu
YunXue Zheng
XiaoYin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1771593

Original Research

Published on 17 Feb 2026

Mechanisms underlying the role of TNF-α and IL-1β preconditioned exosomes derived from human umbilical cord mesenchymal stem cells in wound healing

in Inflammation

Ziyue Zhou
Rui Cao
Lei Shi
Wenhu Jin

Frontiers in Immunology

doi 10.3389/fimmu.2026.1713004

Original Research

Published on 17 Feb 2026

S100A8/A9 inhibition reduces splenic myelopoiesis and improves outcomes after stroke

in Inflammation

Hyun Ah Kim
Annas Al-sharea
Hannah X. Chu
Sung-Chun Tang
Samoda A. Rupasinghe
Shenpeng R. Zhang
Prabhakara R. Nagareddy
Grant R. Drummond
Thiruma V. Arumugam
Andrew J. Murphy

Frontiers in Immunology

doi 10.3389/fimmu.2026.1768647

198 views

Original Research

Published on 17 Feb 2026

Potential of SP1 as a prognostic marker and therapeutic target in acute myocardial infarction: a bioinformatics, Mendelian randomization and experimental validation study

in Inflammation

Zhongyan Li
Huan Cheng
Jingru Li
Xue Guan
Najie Wen
Luqiao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1742618

178 views

5,809 articles

articles

Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery

Stem cell-based therapies for silicosis: mechanisms, sources, clinical translation, and emerging strategies

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

Therapies for bronchiectasis: mechanisms and potential effects

Identification of immune-mediated aging genes associated with cervical spondylosis through single-cell eQTL Mendelian randomization

Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure

Dysregulated hyaluronan metabolism drives inflammation and angiogenesis in proliferative diabetic retinopathy

Integrated transcriptomic and functional analyses reveal that NOX2 inhibition rewires the inflammatory landscape of macrophages

The role of IL-11 in chronic diseases

Identification of FTO as a key m6A demethylase linking immune dysregulation to sepsis pathogenesis

A multi-machine learning framework identifies novel PANoptosis-related biomarkers and their immune landscape in ulcerative colitis: Insights from transcriptomics and experimental validation

Identification of gemilukast as a bifunctional molecule with lipid-lowering and anti-inflammatory activities

Editorial: Lipids in Immunometabolism

Neonatal Pulmonary Vascular Remodeling Induced by Increased Blood Flow Is Associated with an Antiviral-like Immune Signature

Macrophage Plasticity in Thyroid Eye Disease: Dual Effects of Inflammation and Fibrosis

Unveiling the Immune Microenvironment in Diabetic Nephropathy: From Mechanisms to Therapeutics

Aquaporin-4 Suppresses Neuronal Pyroptosis after Ischemic Stroke via the IκBα/NF-κB Signaling Pathway

A Conserved Monocyte Activation Program Links Brain Injury to Systemic Immune Adaptation and Clinical Outcomes

CCS-Mediated Mechanistic Link Between Gestational Diabetes Mellitus and Carpal Tunnel Syndrome: A Multi-Omic MR Framework

Gomphus floccosus (Schw.) Sing. extract attenuates alcoholic liver disease by suppressing macrophage glycolysis and M1 polarization

Amplifying radiation-induced anti-tumor immunity: the dual role of brachytherapy and low-dose total body irradiation

Mechanisms underlying the role of TNF-α and IL-1β preconditioned exosomes derived from human umbilical cord mesenchymal stem cells in wound healing

S100A8/A9 inhibition reduces splenic myelopoiesis and improves outcomes after stroke

Potential of SP1 as a prognostic marker and therapeutic target in acute myocardial infarction: a bioinformatics, Mendelian randomization and experimental validation study