Frontiers in Immunology

Original Research

Published on 09 Sep 2025

TNF-α induces VE-cadherin-dependent gap/JAIL cycling through an intermediate state essential for neutrophil transmigration

in Inflammation

Jan Philip Kipcke
Maria Odenthal-Schnittler
Mohammed Aldirawi
Jonas Franz
Vesna Bojovic
Jochen Seebach
Hans Schnittler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665264

243 views

Original Research

Accepted on 08 Sep 2025

SPP1 as a Biomarker for Idiopathic Membranous Nephropathy Progression and Its Regulatory Role in Inflammation and Fibrosis

in Inflammation

Wei Li
Shuting Pang
Rongbin Zhou
Zige Liu
Boji Xie
Fugang Liu
Bingmei Feng
Xuesong Chen
Liangping Ruan
Hong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671891

Editorial

Accepted on 08 Sep 2025

Editorial: Cholesterol, inflammation and immunity

in Inflammation

Antonio La Cava
Giuseppe Castaldo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696770

Original Research

Accepted on 08 Sep 2025

Neutrophil Extracellular Traps: A Novel Contributor to Vascular Calcification in Chronic Kidney Disease

in Inflammation

Yan Wang
Wenjun Li
Yufeng Liang
Jianxin Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639166

Review

Accepted on 08 Sep 2025

Transient Receptor Potential Channels as Key Regulators of Cell Death in Atherosclerosis

in Inflammation

Yibo Zhang
Weiguo Wang
Xuemin Li
Lei Zheng
Xuewen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661805

Review

Accepted on 08 Sep 2025

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

in Inflammation

Yangyang Zhao
Chunlei Wu
Xiaoxue Liang
Mengjiao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640748

Review

Accepted on 08 Sep 2025

Galectins-1, -3 and -9 in Leukemia: Mechanistic Insights and Therapeutic Translation

in Inflammation

Shaojie Feng
Tianning Wang
Yanxin Zhang
Yuchuan Guo
Mengmeng Zhao
Xiaojun Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685266

Original Research

Accepted on 08 Sep 2025

Identification of anti-mouse PD-1 agonist antibodies that inhibit T cell activation

in Inflammation

Lingling Liu
Shoma Takashima
Yosuke Tokumaru
Naoko Ikuta
Yuka Nakajima
Akio Ohta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631929

Original Research

Accepted on 08 Sep 2025

Higher Aged Neutrophils and Differential Inflammatory Profiles in Sickle Cell Disease Patients on Chronic Transfusion Therapy versus those on Hydroxyurea

in Inflammation

Katrina Terrigno
Zachary Flamholz
Aakash Mahant Mahant
Ilir Agalliu
Jennifer De Los Santos
Karen Ireland
Janine Keenan
Jacob Kazmi
Anayeli Correa
Paul S. Frenette

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671061

Original Research

Published on 08 Sep 2025

Loss of DJ-1 alleviates microglia-mediated neuroinflammation in Parkinson’s disease via autophagy-lysosomal degradation of NLRP3

in Inflammation

Qianqian Miao
Tiantian Wang
Haoran Wang
Yanxia Yu
Xing Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656729

1,647 views

Perspective

Published on 08 Sep 2025

Breaking the cycle: should we target inflammation, fibrosis, or both?

in Inflammation

Sarah K. Baxter
Ricardo A. Irizarry-Caro
Jason A. Vander Heiden
Joseph R. Arron

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569501

437 views

Original Research

Accepted on 05 Sep 2025

Immune-related inflammatory gene in hypertrophic scar: prognostic and molecular mechanisms via integrated machine learning-WGCNA analysis

in Inflammation

Yufang Liu
Huiling Li
Chunfeng Zhao
Wang Xin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645721

553 views

Review

Accepted on 05 Sep 2025

Research Progress of Macrophage Ferroptosis in Inflammatory Bowel Disease and Inflammation-Cancer Transformation

in Inflammation

Siyu Chen
Jing Ma
Junling Tang
Yang Yang
Shiwen Zhou
Peimin Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658280

507 views

Original Research

Published on 05 Sep 2025

Identifying pyroptosis-hub genes and immune infiltration in neonatal hypoxic-ischemic brain injury

in Inflammation

Chi Qin
Yue Li
Meiying Cheng
Huixian Li
Ronghao Mu
Jian Jin
Bohao Zhang
Xin Zhao
Xiaoan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616312

1,392 views

Original Research

Published on 05 Sep 2025

Mesenchymal stem cells enhanced with SeNPs protection against CLP induction associated with liver injury are mediated via antioxidant, anti-inflammatory, and immunomodulatory activities

in Inflammation

Asmaa M. M. Abd El Aleem
Manal F. El-Khadragy
Ahmed E. Abdel Moneim
Sara H. Agwa
Fatma Abou Zahra
Mohga S. Abdalla

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602994

1,416 views

Review

Published on 05 Sep 2025

Inflammation: a key mechanism connecting metabolic-associated steatotic liver disease and systemic arterial hypertension

in Inflammation

Helena Solleiro-Villavicencio
Rebeca Viurcos-Sanabria
José Alfredo Aguayo-Guerrero
Pablo Fernando Pineda-Pérez
Lucía Angélica Méndez-García

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620585

1,383 views