Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Accepted on 19 Sep 2025

circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2

in Cytokines and Soluble Mediators in Immunity

Ming Wu
Yifan Du
Yuyang Dong
Yang Zheng
Lina Gu
Xiaojun Tang
Li Yan
Hong Ji
Yang Sang
Fei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665608

Systematic Review

Accepted on 19 Sep 2025

Interleukin-18 in Lupus Nephritis: a Meta-Analysis of Cytokine Signaling Dysregulation in Immune-Mediated Nephropathy

in Cytokines and Soluble Mediators in Immunity

Cheng Zhou
Jiayi Li
Jing Zhao
Xue-Yuan Bai
Shunlai Shang
Wenge Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631728

Review

Published on 19 Sep 2025

CCR10: a comprehensive review of its function, phylogeny, role in immune cell trafficking and disease pathogenesis

in Cytokines and Soluble Mediators in Immunity

Amanda Lopes Willuveit
Ana Carolina Buzzo Stefanini
Taís Matozo
Luciana Cavalheiro Marti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599277

952 views

Original Research

Published on 18 Sep 2025

Therapy of 4T1 breast cancer in mice with Vaccinia virus encoding tumor-associated antigen epitopes and mouse IL2 cytokine

in Cytokines and Soluble Mediators in Immunity

Mingyu Ye
Ivan Petrov
Ivaylo Gentschev
Eman M. Othman
Aladar A. Szalay

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636256

767 views

Original Research

Accepted on 17 Sep 2025

IL-7 promotes the formation of DNA double strand breaks and DNA repair in murine pro-B cells

in Cytokines and Soluble Mediators in Immunity

Alessia Lamolinara
Chiara Di Lisio
Julie A Hixon
Pasquale Simeone
Antonella De Cola
Maria D Falco
Thomas J Meyer
Alessio Ferrone
Domenico Genovesi
Paola Lanuti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633892

1,282 views

Original Research

Accepted on 17 Sep 2025

Serum IL-17F as a Biomarker of Infection-Independent Cirrhosis Progression

in Cytokines and Soluble Mediators in Immunity

Konstantis Georgios
Moritz Passenberg
Clara Gunltlisbergen
Andreas Schütte
Björn Jung
Nargiz Nuruzade
Florian Seltsam
Dieter Hoyer
Jan Best
Katharina Willuweit

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671288

500 views

Case Report

Accepted on 17 Sep 2025

Longitudinal Mass Cytometry Profiling of a Patient With Disseminated Histoplasmosis and Secondary Hemophagocytic Lymphohistiocytosis

in Cytokines and Soluble Mediators in Immunity

Jiaying Zhang
Longyu Zhang
Zixin Kang
Danlei Mou
Lianchun Liang
Yu Chen
Yingmei Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660382

349 views

Review

Accepted on 17 Sep 2025

The innate immune response in SARS-CoV2 infection: focus on Toll-like Receptor 4 in severe disease outcomes

in Cytokines and Soluble Mediators in Immunity

Enrico Maggi
Nadine Landolina
Francesca Romana Mariotti
Enrico Munari
Nicola Tumino
Paola Vacca
Bruno Azzarone
LORENZO MORETTA

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658396

169 views

Original Research

Accepted on 16 Sep 2025

Integrative genetic and multi-omics analysis reveals the interleukin-6 receptor's role in recurrent spontaneous abortion

in Cytokines and Soluble Mediators in Immunity

Weixu Ma
Zhongjia Gu
Qiwang Lin
Mingzhu Cao
Xin Li
Hongyan Li
Yue Lin
Han Lin
Junmin Zhong
Mengchang Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659251

428 views

Original Research

Accepted on 16 Sep 2025

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

in Cytokines and Soluble Mediators in Immunity

Louise Nuyttens
Marah Heyerick
Maxime Roes
Elise Moens
Céline Van Dender
Charlotte Wallaeys
Tino Hochepied
Steven Timmermans
Jolien Vandewalle
Claude Libert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652516

327 views

Review

Accepted on 16 Sep 2025

Cytokines in Sepsis: A Critical Review of the Literature on Systemic Inflammation and Multiple Organ Dysfunction

in Cytokines and Soluble Mediators in Immunity

Roberta Vella
Diego Panci
Francesco Carini
Ginevra Malta
SALVATORE VIENI
Sabrina David
Giuseppe Davide Albano
Maria Puntarello
Stefania Zerbo
Antonina Argo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682306

314 views

Original Research

Accepted on 12 Sep 2025

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Jiezhong Deng
Jun Gu
Xiaoshan Gong
Hao Tang
Yuyi Cai
Yusheng Yang
Shi-Wu Dong
Chunrong Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630253

1,058 views

Original Research

Published on 12 Sep 2025

Longitudinal evaluation of T-cell responses to Pfizer-BioNTech and Janssen SARS-CoV-2 vaccines as boosters in Ghanaian adults

in Cytokines and Soluble Mediators in Immunity

Frank Osei
Kekeli Korshi Tudzi
Isaac Otieno Othol
Selorm Philip Segbefia
Diana Ahu Prah
Evans Nii Armah-Vedjesu
Abigail Naa Adjorkor Pobee
Oscar Nii Otto Darko
Theophilus Brenko
Doreen Teye-Adjei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643083

1,537 views

Review

Published on 12 Sep 2025

Research progress on the mechanisms of interleukin and chemokine families in driving calcium oxalate nephrolithiasis formation

in Cytokines and Soluble Mediators in Immunity

Fujie Liang
Fuyou Guo
Runjun Liu
Xiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651003

1,019 views

Original Research

Published on 12 Sep 2025

Low rather than high interleukin-6 levels are associated with immune-related adverse events in cancer patients treated with immune checkpoint inhibitors

in Cytokines and Soluble Mediators in Immunity

Iñigo Les
David de Haedo
Mireia Martínez
Berta Ibáñez-Beroiz
Amaia Moreno
Ibone de Elejoste
Ana Campillo-Calatayud
Inés Pérez-Francisco
María Cabero
Iñaki Elejalde

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677778

815 views

Review

Published on 10 Sep 2025

Role of depression-mediated alterations in pro-inflammatory cytokines in carcinogenesis

in Cytokines and Soluble Mediators in Immunity

Rui Cao
Heguo Jiang
Ping Chen
Chunhua Dai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659153

1,450 views