Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Systematic Review

Published on 10 Oct 2025

Interleukin-18 in lupus nephritis: a meta-analysis of cytokine signaling dysregulation in immune-mediated nephropathy

in Cytokines and Soluble Mediators in Immunity

Cheng Zhou
Jiayi Li
Jing Zhao
Xue-Yuan Bai
Shunlai Shang
Wenge Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631728

1,076 views

Original Research

Published on 08 Oct 2025

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

in Cytokines and Soluble Mediators in Immunity

Louise Nuyttens
Marah Heyerick
Maxime Roes
Elise Moens
Céline Van Dender
Charlotte Wallaeys
Tino Hochepied
Steven Timmermans
Jolien Vandewalle
Claude Libert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652516

593 views

Systematic Review

Published on 08 Oct 2025

Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications

in Cytokines and Soluble Mediators in Immunity

Haixia Fan
Bomeng Zhao
Huiyan Niu
Yan Li
Lu Zhai
Limantian Wang
Shudan Deng
Jie Gao
Xiaoling Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677552

1,968 views

Original Research

Published on 08 Oct 2025

circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2

in Cytokines and Soluble Mediators in Immunity

Ming Wu
Yifan Du
Yuyang Dong
Yang Zheng
Lina Gu
Xiaojun Tang
Li Yan
Hong Ji
Yang Sang
Fei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665608

1,143 views

Review

Accepted on 07 Oct 2025

Advances in Immunology of Obstructive Sleep Apnea: Mechanistic Insights, Clinical Impact, and Therapeutic Perspectives

in Cytokines and Soluble Mediators in Immunity

Na Dong
Hongmei Yue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654450

230 views

Original Research

Accepted on 07 Oct 2025

The Power of GM-CSF: Immune Regulation in the Defense Against Phialophora verrucosa Infection

in Cytokines and Soluble Mediators in Immunity

Qi Dong
Jiejie Lu
Mengying Liu
Weiwei WU
Yuying Kang
Ruijun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662183

Review

Published on 07 Oct 2025

The innate immune response in SARS-CoV2 infection: focus on toll-like receptor 4 in severe disease outcomes

in Cytokines and Soluble Mediators in Immunity

Enrico Maggi
Nadine Landolina
Francesca Romana Mariotti
Enrico Munari
Nicola Tumino
Paola Vacca
Bruno Azzarone
Lorenzo Moretta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658396

499 views

Original Research

Published on 06 Oct 2025

IL-7 promotes the formation of DNA double strand breaks and DNA repair in murine pro-B cells

in Cytokines and Soluble Mediators in Immunity

Alessia Lamolinara
Chiara Di Lisio
Julie A. Hixon
Pasquale Simeone
Antonella De Cola
Maria D. Falco
Thomas J. Meyer
Alessio Ferrone
Domenico Genovesi
Paola Lanuti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633892

1,622 views

Editorial

Accepted on 02 Oct 2025

Editorial: Cytokines, and biomarkers involved in the immunomodulation of pediatric cancers

in Cytokines and Soluble Mediators in Immunity

Alessandro Poggi
Gabriella Pietra
Ignazio Caruana
Francesca Romana Mariotti
Bruno Azzarone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713006

144 views

Original Research

Published on 02 Oct 2025

Integrative genetic and multi-omics analysis reveals the interleukin-6 receptor’s role in recurrent spontaneous abortion

in Cytokines and Soluble Mediators in Immunity

Weixu Ma
Zhongjia Gu
Qiwang Lin
Mingzhu Cao
Junmin Zhong
Xin Li
Hongyan Li
Yue Lin
Han Lin
Mengchang Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659251

856 views

Review

Published on 02 Oct 2025

Chemokines as key mediators in RIPI: pathophysiology and translational potential

in Cytokines and Soluble Mediators in Immunity

Ling Zhao
Lihua Dong
Xue Hou
Weijia Fu
Jiaying Wei
Wentong Liu
Wei Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607447

1,809 views

Original Research

Published on 01 Oct 2025

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Jiezhong Deng
Jun Gu
Xiaoshan Gong
Hao Tang
Yuyi Cai
Yusheng Yang
Shiwu Dong
Chunrong Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630253

1,483 views

Case Report

Published on 01 Oct 2025

Case Report: Longitudinal mass cytometry profiling of a patient with disseminated histoplasmosis and secondary hemophagocytic lymphohistiocytosis

in Cytokines and Soluble Mediators in Immunity

Jiaying Zhang
Longyu Zhang
Zixin Kang
Danlei Mou
Lianchun Liang
Yu Chen
Yingmei Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660382

777 views

Original Research

Accepted on 29 Sep 2025

Disrupted macrophage autophagy as a driver of cell death and LPS-induced lethal shock in systemic inflammation

in Cytokines and Soluble Mediators in Immunity

Tarek Chekroune
Sandra Carignon
Meriem Taleb
Stéphanie Rose
Isabelle Mercier
Catherine Mura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610033

678 views

Review

Published on 23 Sep 2025

Chemokines as potential biomarkers for predicting the course of COVID-19 – a review of the literature

in Cytokines and Soluble Mediators in Immunity

Blanka Wolszczak-Biedrzycka
Beata Cieślikiewicz
Filip Studniarz
Łukasz Dąbrowski
Mateusz Fąs
Krystyna Matyszkiewicz–Suchodolska
Monika Harasimowicz
Justyna Dorf

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662643

2,240 views

Original Research

Published on 22 Sep 2025

Extracellular vesicles of patients with acute-on-chronic liver failure induce mitochondrial dysfunction in T cells

in Cytokines and Soluble Mediators in Immunity

Mona-May Langer
Sabrina Guckenbiehl
Alina Bauschen
Helena Stadler
Farnusch Kaschani
Markus Kaiser
Bernd Walkenfort
Heiner Wedemeyer
Christian M. Lange

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656692

1,587 views