Research Topic

Quality of Life and Side Effects Management in Lung Cancer Treatment

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About this Research Topic

Patients with lung cancer experience a plethora of, often complex, treatment side effects that significantly impact their quality of life. These include respiratory symptoms, weight loss, fatigue, sleep difficulties, cognitive dysfunction, pain or neuropathy, as well as psychosocial problems associated with ...

Patients with lung cancer experience a plethora of, often complex, treatment side effects that significantly impact their quality of life. These include respiratory symptoms, weight loss, fatigue, sleep difficulties, cognitive dysfunction, pain or neuropathy, as well as psychosocial problems associated with the course of the disease. With the advances of targeted therapies/immunotherapy, the complexity of side effects has increased (skin problems, pulmonary or cardiac toxicity, diarrhea, etc) and these are poorly documented today with treatment options remaining limited. The financial toxicity of providing supportive care in this population is unknown. To date, the quality of life has received little attention but since patients with lung cancer now live longer due to the availability of more effective treatments, this issue needs to be addressed. Furthermore, the management of such complex symptoms requires a multidisciplinary approach, and the role of the multidisciplinary team in symptom management needs further clarification.

The goal of this Research Topic is to highlight the symptom burden in lung cancer patients, provide evidence of symptom management approaches and explore the impact of the symptoms (and lung cancer treatments in general) to the quality of life.

This Research Topic will focus on the following studies:

1) Observational studies on any of the treatment-related symptoms in lung cancer
2) Exploratory work on symptom clusters in lung cancer
3) Clinical trials of treatment-related symptom management approaches
4) Clinical Guidelines on symptom management from large organisations or societies
5) Quality of life studies in lung cancer patients
6) Impact of symptoms on patients with lung cancer as well as their caregivers/family
7) Financial toxicity of supportive care in patients with lung cancer and cost-effectiveness models or trials
8) Methodological studies on symptoms and quality of life screening and assessment tools, including patient-reported outcome measures
9) Role of multidisciplinary teams in lung cancer symptom management
10) Observational studies related to psychosocial and quality of life issues
11) Palliative care studies related to lung cancer symptoms

Original Research, Reviews, Clinical Trials and Case Reports are particularly sought after. Methods articles on the use of patient-reported outcomes in lung cancer care are also of interest.


Keywords: lung cancer, symptoms management, quality of life, supportive care


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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