About this Research Topic
Therefore, there is an urgent need to identify novel biomarkers that could be used in early diagnosis, guiding initial therapy (both positive and negative predictors) as well as predicting relapse or drug resistance with special regard to new targeted therapies. Without minimizing the importance of other patient-derived samples such as bronchoscopy and lung biopsies, several studies are focusing on the serum as a less invasive material for biomarker identification. Taking advantage of proteomic, transcriptomic and system biology approaches, these emerging studies are focused on soluble proteins, miRNA and circulating DNA.
In this Research Topic we would like to discuss the methods, findings and prospects associated with the discovery of biomarkers that will help in early diagnosis, treatment decisions and drug resistance prediction in lung cancer. Potential topics include but are not limited to the following:
1) New biomarkers for NSCLC for early diagnosis;
2) Biomarkers associated with the use of targeted therapies in NSCLC (including kinase inhibitors)
3) Biomarkers associated with immunotherapy in NSCLC
4) Biomarkers for prediction of drug resistance
5) Next-generation sequencing and its application in diagnosis of NSCLC
The following article types will be considered: Original Research, Review, Mini review, Opinion, Perspective.
Keywords: Biomarkers, Lung Cancer, NSCLC
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