Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity

100.2K

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49

authors

14

articles

Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity

100.2K

views

49

authors

14

articles

Editorial

14 March 2022

Editorial: Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity

Quan Yuan

,

Chun Han

and

Peter Soba

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0 citations

Editors

3

Quan Yuan

National Institute of Neurological Disorders and Stroke (NIH)

Chun Han

Cornell University

Peter Soba

University of Erlangen Nuremberg

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About

Dendrites receive, integrate, and process sensory signals and synaptic inputs. The diverse yet stereotypical nature of their morphology indicates a strong genetic contribution in determining the size and shape of dendritic arbors, while the growth, patterning, and remodeling of the dendrites are among the cellular events most prone to the influences of synaptic activity and experience. Structural and functional modifications of dendrites have a profound impact on circuit connectivity and function and are thus tightly regulated.

This Research Topic aims to answer the following questions:
• How do genetic programs and activity-dependent mechanisms coordinate dendrite morphogenesis and plasticity during development, injury, and repair?
• What are the intrinsic and extrinsic contributions by the network, tissue interaction and sensory input?
• How do changes in dendrite morphology translate into changes in synaptic drive and physiological function?

Answers to these questions are of central interest to basic cellular and developmental neuroscience as well as human neurological diseases such as autism spectrum disorders and neurodegeneration. We welcome original research and reviews that address these questions.

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Editors

Quan Yuan

National Institute of Neurological Disorders and Stroke (NIH)

Chun Han

Cornell University

Peter Soba

University of Erlangen Nuremberg

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68,055 Article views

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Published In

Frontiers in Cellular Neuroscience

Cellular Neurophysiology

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