Research Topic

Management of Diabetes and its Complications: A Focus on Endothelial Dysfunction

About this Research Topic

Endothelial dysfunction refers to the condition in which the endothelium loses its physiological properties. It can be reflected by several pathological conditions, such as abnormities in anticoagulation activities, altered anti-inflammatory function, and impaired modulation of vascular growth. Epidemiological studies have shown that endothelial dysfunction is presented in patients with diabetes and may predict future risk of diabetes. Recent evidence has also pointed out that endothelial dysfunction might be implicated in the pathogenesis and progression of diabetic complications such as cardiovascular events, diabetic retinopathy, diabetic nephropathy, or diabetic foot. As a result, a greater understanding of the association between endothelial dysfunction and diabetes as well as its complications will lead to the development and implementation of more effective interventions.

In this Research Topic, we welcome original research articles (including meta-analyses) or reviews on clinical research, basic human studies, and animal studies, which deal with topics related to diabetes and its complications but with focuses on endothelial dysfunction -- pathogenesis, etiology, epidemiology, assessment, prevention, and treatment.


Keywords: Diabetes, Diabetes Complications, Endothelial Dysfunction, Vascular Growth, Endothelium


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Endothelial dysfunction refers to the condition in which the endothelium loses its physiological properties. It can be reflected by several pathological conditions, such as abnormities in anticoagulation activities, altered anti-inflammatory function, and impaired modulation of vascular growth. Epidemiological studies have shown that endothelial dysfunction is presented in patients with diabetes and may predict future risk of diabetes. Recent evidence has also pointed out that endothelial dysfunction might be implicated in the pathogenesis and progression of diabetic complications such as cardiovascular events, diabetic retinopathy, diabetic nephropathy, or diabetic foot. As a result, a greater understanding of the association between endothelial dysfunction and diabetes as well as its complications will lead to the development and implementation of more effective interventions.

In this Research Topic, we welcome original research articles (including meta-analyses) or reviews on clinical research, basic human studies, and animal studies, which deal with topics related to diabetes and its complications but with focuses on endothelial dysfunction -- pathogenesis, etiology, epidemiology, assessment, prevention, and treatment.


Keywords: Diabetes, Diabetes Complications, Endothelial Dysfunction, Vascular Growth, Endothelium


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 July 2020 Abstract
15 November 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 July 2020 Abstract
15 November 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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