DCLD, mainly due to the widespread use of high-resolution computed tomography. The importance to assess DCLD is based on the fact that approaches and prognosis may vary according to the etiology of such a disorder.
Several original and review articles have been published about DCLDs, addressing diverse issues and etiologies, which determined advances in the understanding of the pathogenesis and in the diagnostic and therapeutic approach. However, there are still many topics that are not fully understood and many of these diseases have not a definitive and curative treatment. Furthermore, there is still no appropriate marker for several DCLDs to determine those patients with a higher risk of progression and death. Therefore, challenges in DCLDs include continuing to improve the advances in pathogenesis, genetics and molecular biology, and finding new diagnostic and prognostic biomarkers, and novel therapeutic options.
This Research Topic aims to update important aspects regarding DCLDs, such as lymphangioleiomyomatosis (LAM), pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dubé syndrome, lymphocytic interstitial pneumonia, pulmonary amyloidosis, bronchiolitis, metastatic neoplasms, smoking-related diseases, and light-chain deposition disease. We also aim to discuss topics that are not fully established and for which there are still doubts. We want to address potentially providing new tools for better understanding of pathogenesis and genetics, and for diagnosis and treatment in such field. , as well as to determine future research directions. The topic also aims to include studies addressing the epidemiology of the different DCLDs and case reports that present new etiologies or rare presentations.
For these purposes, we intend to include original, review and perspective articles, commentaries and remarkable case reports. We hope this Research Topic will provide a broad update in several DCLDs and will determine relevant advances in different aspects in the field.
DCLD, mainly due to the widespread use of high-resolution computed tomography. The importance to assess DCLD is based on the fact that approaches and prognosis may vary according to the etiology of such a disorder.
Several original and review articles have been published about DCLDs, addressing diverse issues and etiologies, which determined advances in the understanding of the pathogenesis and in the diagnostic and therapeutic approach. However, there are still many topics that are not fully understood and many of these diseases have not a definitive and curative treatment. Furthermore, there is still no appropriate marker for several DCLDs to determine those patients with a higher risk of progression and death. Therefore, challenges in DCLDs include continuing to improve the advances in pathogenesis, genetics and molecular biology, and finding new diagnostic and prognostic biomarkers, and novel therapeutic options.
This Research Topic aims to update important aspects regarding DCLDs, such as lymphangioleiomyomatosis (LAM), pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dubé syndrome, lymphocytic interstitial pneumonia, pulmonary amyloidosis, bronchiolitis, metastatic neoplasms, smoking-related diseases, and light-chain deposition disease. We also aim to discuss topics that are not fully established and for which there are still doubts. We want to address potentially providing new tools for better understanding of pathogenesis and genetics, and for diagnosis and treatment in such field. , as well as to determine future research directions. The topic also aims to include studies addressing the epidemiology of the different DCLDs and case reports that present new etiologies or rare presentations.
For these purposes, we intend to include original, review and perspective articles, commentaries and remarkable case reports. We hope this Research Topic will provide a broad update in several DCLDs and will determine relevant advances in different aspects in the field.
