About this Research Topic
Obesity affects nearly one third of children in the United States, and is currently a growing global epidemic that requires attention. Increasing costs in the pediatric health care system relate especially to obese children compared to children with a normal body mass index (BMI). Pediatric obesity is also associated with an increased risk of many other diseases such as diabetes, cardiovascular diseases, metabolic syndrome, certain types of cancer later in life, and social and psychological problems in adolescents and young adults.
The current Research Topic on pediatric obesity intends to incorporate the spectrum of clinical-physiology, social-psychology, and translational research. We would like to include articles covering the following:
• How novel glucose signals can regulate muscle and adipose tissue in insulin resistance in obesity and metabolic syndrome;
• Genetic, immune, and brain-gut models related to obesity diseases;
• Current knowledge on glycoprotein and microbiota research in pediatric obesity;
• Clinical diseases affecting metabolic regulation and endocrine function in children;
• Role of serum fatty acids on subclinical atherosclerosis in obese children;
• Importance of physical activity for prevention of childhood obesity.
• introducing the hypothesis of developmental origin of adult health and disease (DOHaD);
• Elaborating developmental origin of obesity from molecular and environmental aspects;
• Other factors, such as environmental or rural location, and psychological aspect of eating disorder affecting maternal and children body weight and health;
• Policy making for pediatric and adolescent obesity prevention from national governments;
• Adolescent obesity and health; randomized control studies or retrospective cohort studies in school children or young infants, or anthropometric measurement affecting BMI and obesity;
Screening system for metabolically derangements in obese children.
3. Translational research:
• Potential therapy, including how to use cells (iPSC) or genes to treat diabetic and obesity;
• Recent progress on cellular and molecular mechanisms of adipocyte or other related regulation;
• Knowledge or methods to promote adipocyte browning.
In summary, this Research Topic will comprehensively cover all important aspects of current progress in pediatric obesity research.
Keywords: obesity, pediatric obesity, clinical-physiology, social-psychology, translational research
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.