About this Research Topic
All fields of biology have been greatly influenced by the generation of complete and well-annotated genome assemblies. This impact is most apparent with the findings and resulting applications from the Human Genome Project (HGP), which has transformed biomedical science. The original justification for having a genome assembly was to get a complete “parts list” with the primary goal being the identification and location of all genes. However, it soon became readily apparent that genomes were much more than just sequences that code for proteins; protein-coding regions account for ~1.5% of the human genome. Thus, current efforts have been focused on finding relevant functional elements, such as non-coding elements that regulate when, where, and how much specific genes and/or particular isoforms are expressed.
To address the need for annotation of farm animal genomes, the Functional Annotation of Animal Genomes (FAANG) Consortium was launched in 2015. Like other research consortia, FAANG is committed to sharing data rapidly and before publication for the benefit of the whole community (www.faang.org/data-share-principle), with data and metadata (standardized details on samples, laboratory and bioinformatic protocols applied) being collected in the FAANG Data Portal (data.faang.org).
The goal of this Research Topic is to add value to the FAANG community across different farm animal species and topics. We wish to solicit Original Research articles and Commentaries that address efforts to annotate farm animal genomes and inform genomic biology. This includes but is not limited to protocols, results, databases, computational tools, or standards to identify functional elements in both coding and non-coding regions of the genome.
In addition, submissions must be compliant with Frontiers data policy which can be viewed here: https://www.frontiersin.org/about/policies-and-publication-ethics#MandatoryDataRecommendedRepositories.
Keywords: genome annotation, regulatory elements, epigenetics, farm animals
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.