About this Research Topic
Precision medicine aims to tailor pharmacological interventions to the individual, maximizing benefit and reducing adverse events. Enthusiasm for the prospect of precision medicine has grown significantly in the last few years, particularly for immune-mediated disorders. There has been an increasing interest in two advanced topics concerning precision medicine. The first focuses on the integration of patient metadata, electronic medical records capturing longitudinal data and providing clinical phenotypes to establish decision making tools for precision medicine. Secondly, the advance in genomic medicine and pharmacogenomics research provides an expanding arsenal of genetic predictors of diseases and health outcomes. Together, these two streams provide a unique framework for a tailored diagnostic and therapeutic approach to manage the immuno-mediated inflammatory disorders, including inflammatory bowel diseases (IBDs), rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, psoriasis, atopic dermatitis, asthma and chronic obstructive pulmonary disease COPD.
This Research Topic will highlight the most recent advances, obtained either in preclinical and clinical settings, in terms of precision medicine useful for the management of several pathological aspects affecting immuno-mediated inflammatory diseases patients. We specifically would like to integrate advance genomics and cutting-edge technologies to patient’s metadata and known biomarkers of precision medicine to advance tailored therapies to immuno-mediated inflammatory disorders.
To pursue these goals, the present Research Topic will include both full length and short research communications, as well as perspective and review articles.
Keywords: Immune system, inflammation, cytokines, chemokines, fibroblasts
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.