Research Topic

Novel Aspects of Neurotransmitters

About this Research Topic

Neurotransmitters are conventionally viewed as nerve-secreted substances that mediate the stimulatory or inhibitory neuronal functions through binding to their respective receptors. Based on their specific chemical structure, neurotransmitters are divided into three categories: (1) amino acids, including ...

Neurotransmitters are conventionally viewed as nerve-secreted substances that mediate the stimulatory or inhibitory neuronal functions through binding to their respective receptors. Based on their specific chemical structure, neurotransmitters are divided into three categories: (1) amino acids, including acetylcholine (Ach), glutamate, glycine, and gamma-aminobutyric acid (GABA); (2) biogenic amines, including dopamine, norepinephrine (NE), epinephrine (E), and serotonin; (3) peptidergic neurotransmitters termed neuropeptide, including but not limited to substance P (SP), neuropeptide Y (NPY), opioids, calcitonin gene related peptide (CGRP), vasoactive intestinal polypeptide (VIP), bombasin, neurotensin, and many others. In the past decades, many novel discoveries have come to light elucidating the expanded biology of neurotransmitters beyond their traditional role as chemical messengers. Understanding the biology and their clinical relevance of these discoveries is of utmost importance, since this knowledge allows the development of new physiological paradigms and therapeutic approaches.

This Research Topic aims to provide a fundamental presentation of the current status of our understanding of the other non-canonical regulatory roles and molecular mechanisms of neurotransmitters in the physiological functions of cells, tissues, and organs and pathological conditions.

We welcome the submission of Original Research, Methods, Review and Mini-Review articles that cover, but are not limited to the following topics:
- Monoaminylation and its physiological functions
- Roles of neurotransmitter in immune regulation
- Roles of neurotransmitter in metabolic regulation
- Roles of neurotransmitter in gastrointestinal motility
- Roles of neurotransmitter in hematopoiesis, stemness, and regeneration
- Roles of neurotransmitter in tumor initiation and progression


Keywords: Neurotransmitter, Monoaminylation, Immune regulation, Hematopoiesis, Stemness, Tumor development


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

15 February 2021 Manuscript
31 March 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

15 February 2021 Manuscript
31 March 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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