Research Topic

Diabetes, Hypertension and Cardiovascular Diseases

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About this Research Topic

Hypertension and diabetes are common comorbidities and associated with risk of life-threatening cardiovascular diseases (CVD).
The prevalence of type 2 diabetes (T2D) continues to increase worldwide. According to World Health Organization (WHO), the number of cases of T2D has risen from 108 million in ...

Hypertension and diabetes are common comorbidities and associated with risk of life-threatening cardiovascular diseases (CVD).
The prevalence of type 2 diabetes (T2D) continues to increase worldwide. According to World Health Organization (WHO), the number of cases of T2D has risen from 108 million in 1980 to 422 million in 2014 and is expected to grow to 642 million by 2040.


Hypertension is more common, rising in prevalence with a recent estimate of 1.39 billion cases. Diabetes and hypertension are both associated with microvascular and macrovascular diseases and closely related due to similar risk factors such as endothelial dysfunction, vascular inflammation, arterial remodeling, atherosclerosis, dyslipidemia and obesity.


In this Research Topic, we would like to discuss the pathophysiological features of vascular complications associated with diabetes and hypertension. We aim to discuss vascular mechanisms that are involved in both conditions, focusing on inflammation, immune systems, oxidative stress, microRNAs and etc.
Finally, we would like to provide insights into current therapies targeting diabetes, hypertension, and cardiovascular complications.


Keywords: Diabetes, Hypertension, Cardiovascular diseases, Vascular dysfunction, Artery


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