Research Topic

Energy-Sensitive X-Ray Computed Tomography Imaging

About this Research Topic

Energy-sensitive X-ray computed tomography is a very active topic of research in biomedical, clinical, industrial, and security fields. Some of them have changed and benefited our lives greatly, such as dual-energy multi-slice CT in hospitals and dual-energy security CT in airports. Some emerging techniques ...

Energy-sensitive X-ray computed tomography is a very active topic of research in biomedical, clinical, industrial, and security fields. Some of them have changed and benefited our lives greatly, such as dual-energy multi-slice CT in hospitals and dual-energy security CT in airports. Some emerging techniques may soon enter our lives, such as photon-counting spectral CT and dual-MeV-energy container CT. Other techniques, such as X-ray fluorescence CT and inverse Compton scattering X-ray source imaging, are playing important roles in pre-clinical studies and awaiting innovations for wider application.

Over the past decade, there has been steady and great progress in developments of quasi-monochromatic X-ray source, single-photon counting detector, new imaging systems, reconstruction algorithms, material recognition, molecular imaging with various probes, as well as deep learning techniques. Energy-sensitive imaging is becoming the future of clinical X-ray systems, where people are working towards better image quality and lower doses delivered to the patients. Meanwhile, people are also searching for novel applications that can be enabled by new technologies. Compared to MRI, SPECT, and PET, X-ray CT currently has great deficiencies in functional imaging due to its low sensitivity of biomarkers. Energy-sensitive CT, X-ray fluorescence CT, novel molecular contrast agents, and deep learning techniques are expected to increase its sensitivity, making it a good complement to other modalities and enabling new tools to study the biomedical process.

This Research Topic will focus on the current development of energy-sensitive X-ray computed tomography imaging. Manuscript submissions in the related areas are welcome. Potential topics include, but are not limited to:

- Novel applications
- Quasi-monochromatic X-ray source
- Energy-sensitive detector
- System modeling
- Image reconstruction
- Image processing and analysis
- Deep learning techniques
- Contrast agents including nanoparticles, other molecular probes
- Novel systems


Keywords: computed tomography, energy-sensitive, photon counting, spectral imaging, x-ray fluorescence


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

01 March 2021 Manuscript
01 April 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

01 March 2021 Manuscript
01 April 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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