Research Topic

Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans

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About this Research Topic

Toxicology is the science of poisons and arguably the oldest scientific discipline. Globally, human and animal exposures to toxic metals (e.g., arsenic, chromium, lead, mercury, cadmium, and uranium) through water, food and the environment pose major health threat to humans and animals. In particular, ...

Toxicology is the science of poisons and arguably the oldest scientific discipline. Globally, human and animal exposures to toxic metals (e.g., arsenic, chromium, lead, mercury, cadmium, and uranium) through water, food and the environment pose major health threat to humans and animals. In particular, environmental and occupational metal exposures underlie many human and animal diseases.

Knowledge and information sharing on metal-induced toxicity in humans and animals through the avenue of scientific communication is indispensable in addressing these major health concerns associated with heavy metal exposures. Although knowledge on toxic metal has received scientific attention, still more needs to be done in the area of toxic metal exposures, risk assessment, toxicity mechanism,.

The present call in Frontiers in Pharmacology seeks to solicit research works including original research articles, review articles, case reports and other scientific reports on all toxic metal exposures in humans and animals.

Potential topics may include but not limited to:
1. Sources of metal exposures and exposure dynamics.
2. Studies on human and animal poisoning due to exposures to metals such as arsenic, chromium, lead, mercury, cadmium, uranium, copper, iron, and zinc.
3. Effect of metal exposures on the immune, nervous, hepatic, cardiovascular, and the renal systems.
4. Mechanistic elucidation of metal-induced toxicity in humans and animals.
5. Metal chelators.
6. Risk assessment, prevention of toxicity, and detoxification of metal intoxication /management of metal poisoning.


Keywords: Metal, Toxicology, Mechanism, Exposure, Toxicokinetics


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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