About this Research Topic
Stevens-Johnson Syndrome (SJS) is a severely debilitating disease of the skin and mucosal system. It is a multi-system disorder and forms part of the spectrum of disease with toxic epidermal necrolysis (TEN). Acute and chronic management of the SJS patient can be challenging for both the internist, dermatologist, and ophthalmologist. Hence a multidisciplinary team will often have to look after the patient. Much has been learned about underlying genetic risk factors and triggers for the disease. Acute and chronic management of patients with SJS requires extensive reconstruction of both the mucosal surface and skin.
The topic will highlight new therapies and advances in the acute and chronic management of the SJS patient with severe ocular complications. We would like to highlight how early active intervention will improve long-term outcomes, and also visual rehabilitation in these patients. We would also like to cover new advances in biologic therapy, ocular surface treatment in the chronic stage, and gain a better understanding of the ocular microbiome and genetic predisposition in these patients.
We welcome articles related to:
• Advances in the management of ocular surface disease in SJS patients
• Microbiome in SJS patients
• New therapies in improving ocular/skin outcomes in SJS
• Systemic management in SJS patients
• Genomics of SJS
Keywords: Stevens Johnson Syndrome, ocular surface, inflammation, TEN, microbiome
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