About this Research Topic
In recent years, many tools have been developed to directly improve intraoperative tumor visualization. In particular, the use of fluorophores such as 5-ALA, sodium fluorescein and indocyanine green, that can selectively localize in tumor tissue for fluorescence-guided surgery (FGS), represents a promising approach.
The goal of this Research Topic is to provide a comprehensive and up-to-date understanding of the possible utilization of different intraoperative fluorophores for both diagnostic and therapeutic purposes in the field of neuro-oncological surgery, as well as its combined use with other intraoperative tools.
We welcome Original Research, Review and other relevant articles that explore the following non-exhaustive list of themes:
1) The application of 5-ALA, sodium fluorescein, infrared second-window indocyanine green, and targeted fluorophores on biopsies and resection of HGGs and other central and peripheral nervous system tumors;
2) The application of ex-vivo and in-vivo confocal endomicroscopy in neurosurgical oncology;
3) The utilization of different fluorophores for the recognition of intracranial vessels during CNS tumor resection;
4) The development of new fluorophores and new optical devices for possible application in neurosurgical oncology.
Keywords: CNS tumors, fluorescence, 5-ALA, fluorescein, ICG, glioma, glioblastomas, cerebral metastases, spinal cord tumors, brain tumors, neuro-oncology, meningioma, intraoperative imaging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.