About this Research Topic
The rise in the prevalence of allergic diseases and neurodevelopmental disorders has co-occurred in recent decades. Allergic disease manifestations, such as food allergy and asthma, appear to be more common in children with neurodevelopmental disorders compared to their typically developing counterparts. Recent studies have shown that maternal allergy and/or asthma, for example, are associated with neurodevelopmental outcomes like Autism Spectrum Disorder. The immune and neural systems develop over the same time frame in utero and early-life. Thus, there is speculation that immune mechanisms may contribute to both conditions.
There is evidence that children with neurodevelopment disorders, such as Autism Spectrum Disorder, have higher rates of allergic disease and asthma. It is unknown whether these conditions co-occur due to shared causes or exposures or if one of these conditions increases the risk of another. Much of the current work in this area has relied on cross-sectional or case-control studies, which do not allow for the evaluation of potential causal mechanisms. Additionally, limited research has been done to capture biological mediators of these associations, such as markers of the immune system or alterations in the gut microbiome.
• Studies examining allergic disease manifestations in children with neurodevelopmental delays and neurodevelopment in children with allergic diseases
• Studies examining the association of maternal allergic disease markers with neurodevelopment measures in childhood
• Studies attempting to disentangle potential shared causes of childhood allergic disease and altered neurodevelopment
• Studies exploring mechanisms of how maternal prenatal allergic disease measures may impact early childhood neurodevelopment
• A mix of original research, review, and brief report papers are welcome
Keywords: allergies, allergic diseases, neurodevelopmental, autism spectrum disorder
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