Research Topic

Disease Modifying Therapies in Multiple Sclerosis

About this Research Topic

Multiple sclerosis (MS) is an autoimmune central nervous system disease affecting women more than men with increasing incidence in recent years. The disease affects all aspects of life and causes disability and reduced quality of life. Early diagnosis as well as proper treatment could help to control the ...

Multiple sclerosis (MS) is an autoimmune central nervous system disease affecting women more than men with increasing incidence in recent years. The disease affects all aspects of life and causes disability and reduced quality of life. Early diagnosis as well as proper treatment could help to control the disease activity and delay progression of the disease.

Disease modifying treatments affect immune system by modulation or suppression and are useful for controlling the disease activity. They could control disease activity and relapse rate and improve quality of life. These medications are not neuroprotective and do not play a role in neural repair.

In this Research Topic, we will focus on DMTs, their efficacy and safety profiles, their adverse effects, and their administration to patients with different levels of disability. We also appreciate comparison of different medications and their effects on relapse rate, Expanded Disability Status Scale (EDSS), and number of plaques in magnetic resonance imaging (MRI) assessment. Pregnancy with DMTs is also a concern that needs to be addressed. We hope that this topic can shed light on the use of diseases modifying treatments in MS for neurologists, MS fellowships, and neurology residents, to improve treatment of MS patients. We welcome submissions of high quality and well-designed manuscripts which add information to current knowledge.

For this Research Topic we welcome manuscripts on the following themes:
• Efficacy and safety profiles of DMTs;
• Adverse effects;
• Persistence of the patients;
• Pregnancy with DMTs;
• Vaccination and DMTs;
• Treatment delay.


Keywords: Multiple sclerosis, Disease modifying therapies, efficacy, safety


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

08 March 2021 Manuscript
07 April 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

08 March 2021 Manuscript
07 April 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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