Research Topic

Cholangiocarcinoma: A New Multimodality Approach

About this Research Topic

Cholangiocarcinoma (CCA) is the second leading cause of primary liver cancer in the world. In the last five years the approach to CCA has moved toward radiological and histological diagnosis and treatment. CCA is often asymptomatic in its early stages, therefore it is usually only diagnosed in advanced stages, with Jaundice due to biliary obstruction being a common symptom. Considering this, CCA requires a multimodality approach to diagnosis and treatment. Information about the site, dimension, stage and histology are provided by radiologists and pathologists, and are vital to be able to begin treatment. However, the jaundice requires specific treatment before starting chemotherapy; endoscopists and interventional radiologists play a key role in these cases.

The goal of this Research Topic is to look at the multidisciplinary management of cholangiocarcinoma, advancements in the diagnosis and treatment, and define a new alliance for CCA. We welcome the submission of Original Research and Review Articles covering, but not limited, to the following subtopics:
- Pathogenesis and molecular pathway
- Advancements in Cholangiocarcinoma histopathology
- The role of endoscopy in cholangiocarcinoma
- Interventional radiology for the management of cholangiocarcinoma
- Chemotherapy: the old and the new treatments
- Gastroenterologist, Oncologist, Endoscopist and Radiologist, alliance for the treatment


Keywords: cholangiocarcinoma, jaundice, CCA, endoscopists, liver cancer, multimodal


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Cholangiocarcinoma (CCA) is the second leading cause of primary liver cancer in the world. In the last five years the approach to CCA has moved toward radiological and histological diagnosis and treatment. CCA is often asymptomatic in its early stages, therefore it is usually only diagnosed in advanced stages, with Jaundice due to biliary obstruction being a common symptom. Considering this, CCA requires a multimodality approach to diagnosis and treatment. Information about the site, dimension, stage and histology are provided by radiologists and pathologists, and are vital to be able to begin treatment. However, the jaundice requires specific treatment before starting chemotherapy; endoscopists and interventional radiologists play a key role in these cases.

The goal of this Research Topic is to look at the multidisciplinary management of cholangiocarcinoma, advancements in the diagnosis and treatment, and define a new alliance for CCA. We welcome the submission of Original Research and Review Articles covering, but not limited, to the following subtopics:
- Pathogenesis and molecular pathway
- Advancements in Cholangiocarcinoma histopathology
- The role of endoscopy in cholangiocarcinoma
- Interventional radiology for the management of cholangiocarcinoma
- Chemotherapy: the old and the new treatments
- Gastroenterologist, Oncologist, Endoscopist and Radiologist, alliance for the treatment


Keywords: cholangiocarcinoma, jaundice, CCA, endoscopists, liver cancer, multimodal


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

05 April 2021 Manuscript
05 May 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

05 April 2021 Manuscript
05 May 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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