About this Research Topic
This Research Topic is devoted to the shared and distinct mechanisms underlying migraine and stroke. The comparative study of cellular and molecular mechanisms of migraine and stroke should advance our understanding of their complex nature and yield new pharmaceutical targets for both disorders. We welcome submissions of original research articles and review papers addressing, but not limited to, the following subtopics:
• CSD mechanisms, triggers, propagation, cellular/network impact
• Cortical spreading depolarization (CSD) in migraine and peri-infarct depolarizations (PID) in stroke: what is common?
• Preconditioning for brain tolerance and activation of neurogenesis by CSD.
• A mechanistic rationale for management of the ischemic penumbra.
• Migraine and stroke: are there shared genetic factors?
• Genetic mouse models of stroke and migraine: what did we learn?
• Brain-on-a-chip: a novel avenue for research on migraine and stroke?
• Neuroinflammation and immune responses in migraine and stroke.
• Clotting disturbances in migraine and stroke.
• Mechanisms of Covid19 induced neurological symptoms, stroke and headache.
• Homocysteine as a link between migraine with aura and ischemic stroke
• Role of glial cells in migraine and stroke.
• Oxidative stress in migraine and stroke.
• Headache after stroke: what are the mechanisms?
• Disrupted BBB integrity in migraine and stroke?
• Gender-dependence of migraine and stroke.
• Cellular and molecular mechanisms of ‘Migrainous Infarction’ and microlesions in migraine.
• Repurposing of perspective anti-migraine drugs for stroke and vice versa, any perspective, any risks?
Keywords: Migraine, stroke, neuron, spreading depression, headache
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.