Research Topic

Psychological-Behavioral and Lifestyle Risk Factors of Cognitive Decline

About this Research Topic

Cognitive functions are deeply affected by aging. Cognition can occur due to neurodegenerative, vascular, and behavior problems. Impaired cognition can affect social, functional, and occupational activities. Albeit the greatest risk factor for cognitive decline is age, there are many others, such as psychological (stress, depression, neuroticism etc.) or lifestyle (physical activity, socioeconomic status, educational level etc.) factors whose effect needs to be considered.

In the field of precision medicine, the early identification of people at risk of cognitive decline is essential in order to implement specific therapies and personalized treatments focused on the individual case or appropriate care pathways. In the context of prevention, it is essential to identify the cognitive-behavioral variables that could manifest themselves in the prodromal phase of dementia and have an impact on the cognitive path.

The onset of cognitive decline often precedes the clinical manifestation by many years, intertwining with the phenomena of physiological aging. It is important to identify risk factors for cognitive decline across its entire spectrum from subjective cognitive disorder to dementia for prevention and early intervention.

The goal of this Research Topic is to examine risk factors for cognitive impairment in order to implement effective preventive strategies. We aim at collecting a complete body of research on psychological-behavioral and lifestyle risk factors in cognitive decline answering the following questions:
-what are the psychological factors that increase the risk of cognitive decline?
-are there protective psychological factors of cognitive decline?
-are there behavioral traits that predispose to dementia characterized by neuropsychiatric disorders?
-Which variables define the lifestyle or cognitive reserve?
-Are there any lifestyle variables that are more protective than others?

We welcome manuscripts with a conceptual or methodological focus and papers reporting original data addressing the following subtopics:

• Psychological and personality traits as prodromes of cognitive impairment not dementia;
• Psychological factors associated with mood alterations in cognitive decline;
• Relationship between premorbid behavioral trait and behavioral disorder in dementia;
• Traits personality associated with a higher risk of dementia;
• Assessment tools of personality traits in cognitive impairment;
• Lifestyle components as a protective factor against the development of cognitive decline;
• Lifestyle measured by cognitive reserve indices in general population;
• Association between personality traits and lifestyle;
• Studies of personality as predictors of the rate of cognitive decline in older adults;
• associated with measures of whole brain;
• association between mood or personality changes and cognitive decline in organic diseases.


Keywords: cognitive decline, lifestyle risk factors, older adults, aging, dementia, neuropsychiatric disorders


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Cognitive functions are deeply affected by aging. Cognition can occur due to neurodegenerative, vascular, and behavior problems. Impaired cognition can affect social, functional, and occupational activities. Albeit the greatest risk factor for cognitive decline is age, there are many others, such as psychological (stress, depression, neuroticism etc.) or lifestyle (physical activity, socioeconomic status, educational level etc.) factors whose effect needs to be considered.

In the field of precision medicine, the early identification of people at risk of cognitive decline is essential in order to implement specific therapies and personalized treatments focused on the individual case or appropriate care pathways. In the context of prevention, it is essential to identify the cognitive-behavioral variables that could manifest themselves in the prodromal phase of dementia and have an impact on the cognitive path.

The onset of cognitive decline often precedes the clinical manifestation by many years, intertwining with the phenomena of physiological aging. It is important to identify risk factors for cognitive decline across its entire spectrum from subjective cognitive disorder to dementia for prevention and early intervention.

The goal of this Research Topic is to examine risk factors for cognitive impairment in order to implement effective preventive strategies. We aim at collecting a complete body of research on psychological-behavioral and lifestyle risk factors in cognitive decline answering the following questions:
-what are the psychological factors that increase the risk of cognitive decline?
-are there protective psychological factors of cognitive decline?
-are there behavioral traits that predispose to dementia characterized by neuropsychiatric disorders?
-Which variables define the lifestyle or cognitive reserve?
-Are there any lifestyle variables that are more protective than others?

We welcome manuscripts with a conceptual or methodological focus and papers reporting original data addressing the following subtopics:

• Psychological and personality traits as prodromes of cognitive impairment not dementia;
• Psychological factors associated with mood alterations in cognitive decline;
• Relationship between premorbid behavioral trait and behavioral disorder in dementia;
• Traits personality associated with a higher risk of dementia;
• Assessment tools of personality traits in cognitive impairment;
• Lifestyle components as a protective factor against the development of cognitive decline;
• Lifestyle measured by cognitive reserve indices in general population;
• Association between personality traits and lifestyle;
• Studies of personality as predictors of the rate of cognitive decline in older adults;
• associated with measures of whole brain;
• association between mood or personality changes and cognitive decline in organic diseases.


Keywords: cognitive decline, lifestyle risk factors, older adults, aging, dementia, neuropsychiatric disorders


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

23 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

23 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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