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Clinical research is an essential domain in Life Sciences that mainly attracts the interest of sponsors. In the past few years, there are efforts to harmonize clinical trials with the evolution of Internet of Things (IoT) and Artificial Intelligence (AI) and by means of patient-centric applications to collect ...

Clinical research is an essential domain in Life Sciences that mainly attracts the interest of sponsors. In the past few years, there are efforts to harmonize clinical trials with the evolution of Internet of Things (IoT) and Artificial Intelligence (AI) and by means of patient-centric applications to collect Real World Data (RWD) that can optimize the clinical trial processes, while obtaining useful insights.

The clinical research domain lags behind the digital era and is still decoupled from digital services. The goal is to identify innovations that can push clinical research to its boundaries, resulting in personalized interventions of higher efficacy that can be linked with digital services. These innovations should be put under a regulatory framework, so as to enable a shorter time-to-market for the benefit of the patients.

Topics covered may include:

• Discovery of digital biomarkers from RWD and their application in eHealth applications;
• IoT devices to capture for RWD;
• AI processing of RWD in SaMD (Software as for Medical Devices);
• Virtual Coaching as digital intervention;
• Impact of AI and RWD in Digital Therapeutics (DTx)


Dr. Sofoklis Kyriazakos is the founder and CEO of Innovation Sprint. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Keywords: RWD, RWE, AI, DTx, biomarkers, lifestyle


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