About this Research Topic
Clearly, many variables (e.g. exercise mode, frequency, duration and intensity) may affect the results. Moreover, women and men exhibit many gender-specific anthropometric and physiologic characteristics, which may influence these adaptive mechanisms and therefore, performance. However, this aspect in particular has often been overlooked. For example, it is known that in long-term endurance exercise, women perform similarly or slightly better than men while in quick bursts with great power no, suggesting a distinct gender dimorphism in metabolism. What molecular mechanisms are activated in man and woman in response to physical exercise? And in recovery, do they act similarly? What about the gender dimorphism in terms of proteomics, lipidomics and metabolomics? What benefits arise from physical activity as an expression and activation of molecular mechanisms? Unfortunately, till now, women are still under-represented compared to men in sport and exercise research, therefore, a comparison to highlight the gender specific adaptation to physical exercise is difficult to do. Generally, data on sex hormonal status are lacking. Instead, hormonal signalling together with muscle fiber type composition and oxidative stress are very important features that characterize gender response in sports. Thus, more studies are needed to fully understand the gender specific physiology and metabolism response during exercise.
In this context, this Research Topic seeks research articles and reviews on a broad range of topics in the area of “woman and man in physical activity” including:
· Gender muscle fiber type composition
· Gender related differences in cellular and molecular biomarkers (with particular relevance to those belonging to redox/inflammatory pathways) as a response to exercise (according to type, intensity, frequency and duration)
· Cardiometabolic response to different exercise mode, frequency, duration and intensity according to gender
· Gender differences in hormonal signals associated to exercise
Keywords: Physical exercise, training, gender, oxidative stress, inflammation, omics sciences
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.