About this Research Topic
Hearing is one of the most important senses of humans. It enables us to connect to the world, which is essential for maintaining the quality of daily life. It is estimated that more than one billion people worldwide are suffering from different types of hearing loss. In the last decade, emerging evidence shows that hearing loss plays a vital role in the development and progression of cognitive disorders, such as dementia, autism, and Alzheimer’s disease. A number of studies have revealed that the central auditory system and the limbic system, such as the hippocampus and the frontal cortex are involved in speech processing in noise, sound perception and emotional changes. For example, the hippocampus is involved in auditory working memory such as encoding, signal maintenance and retrieval, and become more active in people with age related hearing loss. However, our understanding of the mechanisms linking hearing loss and cognitive disorders are still limited. Cochlear implant in hearing-impaired elderly patients has revealed excellent improvement to both speech perception and cognition. Therefore, investigating the role of hearing loss on brain structure and cognitive dysfunction will help us to understand the pathogenesis of cognitive disorders, which may shed light on novel approaches for developing therapeutic strategies for cognitive disorders.
In this Research Topic, we aim to encourage discussions and welcome new findings contributing to the 3 main goals:
1) to identify novel links between peripheral auditory disorders and cognitive deficits;
2) to investigate biological mechanisms underlying the hearing loss induced cognitive dysfunction, and
3) to explore the potential effects of hearing restoration on the recovery of cognitive deficits.
Of note, both basic and clinical studies will be welcomed in this Research Topic.
Keywords: Hearing Loss, Presbycusis, Cochlear Damage, Cognitive Disorder, Hippocampus
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