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Medically refractory chronic and cancer-related pain can significantly reduce one's quality of life. Further advancements in therapies meant to mitigate pain and reduce systemic opioid requirements are necessary to reduce patient suffering and opioid-induced side effects.

This topic aims to ...

Medically refractory chronic and cancer-related pain can significantly reduce one's quality of life. Further advancements in therapies meant to mitigate pain and reduce systemic opioid requirements are necessary to reduce patient suffering and opioid-induced side effects.

This topic aims to encourage and disseminate high-quality pioneering research related to pain surgery techniques for the treatment, management of chronic and cancer-related pain, in addition to improving our understanding of neuroanatomy and pain transmission.

Research that furthers our current management by demonstrating clinical success and enhancing our knowledge of pain mechanisms are of interest.

Topic considerations include studies focused on intrathecal medication administration, invasive neurostimulation such as:

• Spinal cord and peripheral nerve stimulation
• Craniofacial and spinal cord lesional therapies
• Neuroanatomy
• Mechanisms of pain transmission and modulation.

The editors welcome clinical and basic human experimental research, including but not limited to randomized trials, observational studies, reviews, and opinion articles.

Keywords: Neuromodulation, Neurosurgery, Chronic Pain, Cancer Pain, Pain Surgery


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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