About this Research Topic
The aims of this Research Topic is to gain an improved understanding of CSVD in terms of the physiologies and pathologies, neurological mechanism, potential markers, and assessing or diagnostic techniques, using neuroimaging methods (e.g. CT, MRI, PET-CT/MRI), from basic to clinical research, from population/patient-based studies to animal models.
The sub-topics within the scope include, but are not limited to the following:
1) Imaging and quantifying the structural and functional alterations in the brain;
2) Developing imaging markers in improving early diagnoses and differential diagnoses,
3) Understanding of pathophysiologic mechanisms of CSVD and how its association with Stroke, Cognitive impairment, gait and balance disorders, and etc.
4) Neuroimaging assessment and prediction of the progression and severity of CSVD
5) Evaluation of pharmacological/non-pharmacological interventions, and treatment efficacy via neuroimaging approaches
6) improvement and refinement of neuroimaging techniques and data analysis, e.g. multimodal approaches, machine-learning based approaches
Original articles, Review articles, case reports, protocols, clinical trials, systematic reviews and meta-analyses are welcome.
Keywords: CSVD, CT, PET, MRI, Imaging markers
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.