Research Topic

Coronary epicardial and microvascular hemodynamics

About this Research Topic

Recent large trials question the impact of percutaneous coronary interventions in improving patients´ prognosis, such that there is a growing need for methods that assess more precisely which patients and lesions deserve intervention. Methods for the invasive or non-invasive assessment of coronary physiology are well established in clinical routine, and their use is steadily expanding. However, a number of questions still remain. These pertain, among many other, the relative merits of hyperemia-based versus resting indexes, the relationship with imaging methods, the impact of post-PCI hemodynamics, scenarios of complex anatomies (e.g. tandem or diffuse stenosis), the role of the microcirculation, the best strategies to treat microvascular dysfunction, the impact of non-invasive or less-invasive technologies and of medical or interventional therapies on coronary hemodynamics. This research topic welcomes original research, reviews, clinical case reports which provide address the above mentioned questions.


Keywords: fractional flow reserve, coronary microcirculation, resting indexes, quantitative flow reserve, intracoronary imaging


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent large trials question the impact of percutaneous coronary interventions in improving patients´ prognosis, such that there is a growing need for methods that assess more precisely which patients and lesions deserve intervention. Methods for the invasive or non-invasive assessment of coronary physiology are well established in clinical routine, and their use is steadily expanding. However, a number of questions still remain. These pertain, among many other, the relative merits of hyperemia-based versus resting indexes, the relationship with imaging methods, the impact of post-PCI hemodynamics, scenarios of complex anatomies (e.g. tandem or diffuse stenosis), the role of the microcirculation, the best strategies to treat microvascular dysfunction, the impact of non-invasive or less-invasive technologies and of medical or interventional therapies on coronary hemodynamics. This research topic welcomes original research, reviews, clinical case reports which provide address the above mentioned questions.


Keywords: fractional flow reserve, coronary microcirculation, resting indexes, quantitative flow reserve, intracoronary imaging


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 May 2021 Abstract
30 September 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 May 2021 Abstract
30 September 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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