A Changing Epidemic and the Rise of Opioid and Stimulant Co-Use

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Editorial

06 July 2022

Editorial: A Changing Epidemic and the Rise of Opioid-Stimulant Co-Use

Saeed Ahmed

,

Zouina Sarfraz

and

Azza Sarfraz

9,687 views

27 citations

Editors

3

Justin Strickland

Johns Hopkins Medicine, Johns Hopkins University

Kelly E Dunn

School of Medicine, Johns Hopkins University

Saeed Ahmed, MD, FAPA, FASAM

Saint Francis Hospital and Medical Center

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About

There has been a significant and rapid increase in the co-use of stimulants and opioids in the US in the past year, being referred to as the 4th wave of the opioid epidemic. Co-use is leading to increased rates of drug poisonings and is made more challenging by the lack of treatment available for stimulant use disorder. There are compelling preclinical data suggesting that sensitivity to dopaminergic drugs, such as stimulants, is increased after chronic exposure to opioid medications. This may be contributing to the escalating rates of abuse being observed. However these data have not yet been cohesively organized.

Our aim with this Research Topic is to curate a translational collection that covers preclinical and human clinical evidence of stimulant-opioid interactions, summarizes known challenges regarding treatment, and outlines morbidity and mortality. The goal would be to bring this issue to the forefront early in this epidemic to help mobilize researchers and clinicians around this collection.

Potential topics could include:
• Electrophysiological evidence
• Preclinical animal behavioral evidence
• Evidence of human co-use patterns
• Commentary outlining challenges for treatment
• Examples of co-treatments
• Epidemiological discussion of morbidity and mortality
• Epidemiological presentation of co-use patterns and changes over time

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Editors

Justin Strickland

Johns Hopkins Medicine, Johns Hopkins University

Kelly E Dunn

School of Medicine, Johns Hopkins University

Saeed Ahmed, MD, FAPA, FASAM

Saint Francis Hospital and Medical Center

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65,483 Total views

50,945 Article views

12,830 Article downloads

1,708 Topic views

Published In

Frontiers in Psychiatry

Addictive Disorders

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