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Athlete’s heart has been regarded as a benign process of cardiac remodeling related to heavy physical training. Several electrocardiographic changes such as first-degree atrioventricular block and left ventricular hypertrophy are prevalent in athletes. In cardiac imaging studies, athletes have greater chamber ...

Athlete’s heart has been regarded as a benign process of cardiac remodeling related to heavy physical training. Several electrocardiographic changes such as first-degree atrioventricular block and left ventricular hypertrophy are prevalent in athletes. In cardiac imaging studies, athletes have greater chamber sizes and more effective diastolic function than sedentary individuals.

Previous studies have demonstrated racial differences in the cardiac adaptions to exercise and to left ventricular pressure overload. For given levels of training, athletes of African/ Afro-Caribbean descent reveal more marked morphologic changes than Caucasian athletes, which is likely due in part to genetic factors. In addition, the cardiac remodeling in male athletes is greater than that in female athletes. However, there have only been a few studies investigating cardiovascular health in Asian athletes and in specific subgroups such as military individuals who receive regular training but are exposed at high risk of psychological stress and metabolic abnormalities.

The purpose of this Research Topic is to understand the advances in knowledge concerning the mechanisms underlying the racial and sex differences in the association of physical fitness and cardiovascular health. In addition, population-based studies for subgroups which are rarely investigated, such as Asian athletes and military individuals, are welcome. 

We expect submissions examining the mechanisms of the genetic expressions, molecular pathways, stem cell production and environmental interactions on cardiac remodeling and electrocardiographic changes among diverse athlete subgroups and physically active individuals at high cardiovascular risk.

We welcome manuscripts of all types, including Original Research and Reviews, aimed at assessing sex- and race-specific mechanisms of cardiac adaptations to regular exercise, particularly in Asian and military individuals. We would like to encourage multidisciplinary efforts in including basic and clinical data, in line with the logic “from bench to bed – and return”.

Submissions on, but not limited to, the following topics will be considered:
1) The sex-specific mechanisms of exercises on cardiac remodelling.
2) The sex-specific mechanisms of exercises on electrocardiographic changes.
3) The race-specific mechanisms of exercises on cardiac remodelling.
4) The race-specific mechanisms of exercises on electrocardiographic changes. 
5) The association of physical fitness with cardiac remodelling in the military.
6) The association of physical fitness on electrocardiographic changes in the military.
7) The effect of metabolic abnormalities on the association of physical fitness with cardiac remodelling in athletes of diverse ethnicities or military individuals.
8) The effect of metabolic abnormalities on the association of physical fitness with electrocardiographic changes in athletes of diverse ethnicities or military individuals.
9) The clinical prognosis of cardiovascular health related to physical fitness in athletes of diverse ethnicities or military individuals

Keywords: Athlete's heart, cardiovascular health, cardiac remodeling, metabolic abnormalities, physical fitness, specific populations


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