Clinicopathological Factors and Staging in Gastrointestinal Cancers

241.7K

views

526

authors

74

articles

Clinicopathological Factors and Staging in Gastrointestinal Cancers

241.7K

views

526

authors

74

articles

Editorial

05 April 2023

Editorial: Clinicopathological factors and staging in gastrointestinal cancers

Ravindra Deshpande

1,102 views

0 citations

Editors

5

Shanghai Cancer Center, Fudan University

Pusan National University Hospital

Shouki Bazarbashi

King Faisal Specialist Hospital and Research Centre

Ravindra Deshpande

School of Medicine, Wake Forest University

Sanjit Mukherjee

National Institutes of Health (NIH)

Impact

Fetching...

About

Gastrointestinal (GI) cancers are among the most common types of malignant tumor. Presently, GI cancers are staged according to a system designed by the American Joint Committee on Cancer (AJCC) that defines the prognosis in a clear manner and is thus used for clinical treatment decisions. The AJCC staging system differentiates patients on the basis of the invasion extent of primary tumor (T-stage), lymph node status (N-stage), and distant spread (M-stage). However, the TNM staging system is not perfect for the prognosis prediction and clinical management of GI cancers. The AJCC has once issued a request for proposals to develop staging methods based on other available information beyond the classical TNM staging.

Although several modifications in the past years have improved its predictive ability, the AJCC staging system is not perfect for the prognosis prediction. In addition to the invasion extent of primary tumor, lymph node status, and distant spread, many clinicopathological factors have been shown to impact on the prognosis of GI cancers, such as microenvironmental markers, treatment effect, gene mutations and circulating biomarkers. Therefore, this research topic focuses on the staging and prognosis prediction of different clinicopathological factors in GI cancers.

We welcome original research articles, short communications, and review articles covering, but not limited to, the following topics:
• The refinement of GI cancer staging system
• Prognostic predictionbased on GI cancer staging
• Survival analyses of clinicopathological factors in GI cancers
• Treatment choices in GI cancers.

Gastrointestinal (GI) cancers are among the most common types of malignant tumor. Presently, GI cancers are staged according to a system designed by the American Joint Committee on Cancer (AJCC) that defines the prognosis in a clear manner and is thus used for clinical treatment decisions. The AJCC staging system differentiates patients on the basis of the invasion extent of primary tumor (T-stage), lymph node status (N-stage), and distant spread (M-stage). However, the TNM staging system is not perfect for the prognosis prediction and clinical management of GI cancers. The AJCC has once issued a request for proposals to develop staging methods based on other available information beyond the classical TNM staging.

Although several modifications in the past years have improved its predictive ability, the AJCC staging system is not perfect for the prognosis prediction. In addition to the invasion extent of primary tumor, lymph node status, and distant spread, many clinicopathological factors have been shown to impact on the prognosis of GI cancers, such as microenvironmental markers, treatment effect, gene mutations and circulating biomarkers. Therefore, this research topic focuses on the staging and prognosis prediction of different clinicopathological factors in GI cancers.

We welcome original research articles, short communications, and review articles covering, but not limited to, the following topics:
• The refinement of GI cancer staging system
• Prognostic predictionbased on GI cancer staging
• Survival analyses of clinicopathological factors in GI cancers
• Treatment choices in GI cancers.

Download ebook

Share

Editors

Shanghai Cancer Center, Fudan University

Pusan National University Hospital

Shouki Bazarbashi

King Faisal Specialist Hospital and Research Centre

Ravindra Deshpande

School of Medicine, Wake Forest University

Sanjit Mukherjee

National Institutes of Health (NIH)

Impact

241,689 Total views

162,658 Article views

76,606 Article downloads

2,425 Topic views

Published In

Journal Thumbnail

Frontiers in Oncology

Surgical Oncology, Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Journal Thumbnail

Frontiers in Surgery

Surgical Oncology

Journal Thumbnail

Frontiers in Medicine

Gastroenterology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic