Nanovesicle-based therapeutic, prevention and detection modalities have the potential to greatly impact diagnosis and management of diseases in the clinic. Nanovesicles can be natural vesicles that are secreted by cells (extracellular vesicles) with a diameter of 100-1000 nm. Such vesicles play a vital role not only in regulating normal physiological processes, such as stem cell maintenance, tissue repair and immune modulation, but also in the pathology underlying the occurrence of various disorders. Nanovesicles can also be directly obtained from cells by top-down technique. Such vesicles have been widely used for disguising and encapsulating nanoparticles. Based on this, the cell membrane coating nanotechnology was developed. No matter what forms of nanovesicles, they can be used in drug delivery, immune modulation, and detection, etc. Importantly, this cell-derived nanocarrier can be combined with traditional nanomedicine and has broad prospects in the establishment of next-generation theranostic nanoplatforms.
This Research Topic aims to explore the construction of nanovesicles-based theranostic nanoplatform in metabolic diseases. A spectrum of research interests will be covered to reveal the formation, biological function, and biomedical applications of nanovesicles.
Novel studies (original research and reviews) of nanovesicles with roles in metabolic diseases, such as diabetes, arthritis, and other diseases related to inflammation and dysfunctional immune responses, are welcome.
Potential topics include, but are not limited to:
1) Novel treatments of nanovesicles for metabolic disease.
2) Novel development of nanovesicle-based platforms for regulating cell metabolism.
3) Basic and preclinical studies that help reveal the physiological and pathological roles of nanovesicles in metabolic disease.
Nanovesicle-based therapeutic, prevention and detection modalities have the potential to greatly impact diagnosis and management of diseases in the clinic. Nanovesicles can be natural vesicles that are secreted by cells (extracellular vesicles) with a diameter of 100-1000 nm. Such vesicles play a vital role not only in regulating normal physiological processes, such as stem cell maintenance, tissue repair and immune modulation, but also in the pathology underlying the occurrence of various disorders. Nanovesicles can also be directly obtained from cells by top-down technique. Such vesicles have been widely used for disguising and encapsulating nanoparticles. Based on this, the cell membrane coating nanotechnology was developed. No matter what forms of nanovesicles, they can be used in drug delivery, immune modulation, and detection, etc. Importantly, this cell-derived nanocarrier can be combined with traditional nanomedicine and has broad prospects in the establishment of next-generation theranostic nanoplatforms.
This Research Topic aims to explore the construction of nanovesicles-based theranostic nanoplatform in metabolic diseases. A spectrum of research interests will be covered to reveal the formation, biological function, and biomedical applications of nanovesicles.
Novel studies (original research and reviews) of nanovesicles with roles in metabolic diseases, such as diabetes, arthritis, and other diseases related to inflammation and dysfunctional immune responses, are welcome.
Potential topics include, but are not limited to:
1) Novel treatments of nanovesicles for metabolic disease.
2) Novel development of nanovesicle-based platforms for regulating cell metabolism.
3) Basic and preclinical studies that help reveal the physiological and pathological roles of nanovesicles in metabolic disease.