Research Topic

Non-invasive Brain Stimulation in the Developing and Aging Brain

About this Research Topic

Non-invasive brain stimulation (NIBS) has become a popular tool in neuroscience, as a method to study the brain (e.g. neurophysiology and cognition) or as a treatment for neurological conditions (e.g. mental health disorders). There are a growing range of NIBS techniques that deliver transcranial stimulation (e.g. magnetic, electrical and ultrasound stimulation) which have been shown to be effective in altering neural activity or plasticity in animal models and humans.

Despite the wide use of NIBS in basic and clinical neuroscience, the majority of NIBS protocols, cellular mechanisms and efficacy have been investigated in the young adult brain. Given the clear anatomical and physiological differences that occur in the brain across the lifespan, it is likely that the evidence from young adults cannot be generalized to all ages. Therefore, there is a critical need to characterize and optimize the use of NIBS in younger and older brains to develop more effective stimulation protocols and treatment strategies for these demographics.

We seek submissions that investigate the effect of NIBS in the developing and aged brain from gene expression and single cells (neurons and glia) to neural networks and behavior. Studies using human participants (clinical and pre-clinical populations), animals models as well as theoretical and computational models are encouraged. We welcome manuscripts in any of the accepted article formats (e.g. original articles, data reports, technology report, opinion pieces or mini-reviews).


Keywords: Transcranial magnetic stimulation, Transcranial electrical stimulation, Transcranial ultrasound stimulation, Static magnetic stimulation, Aging, Development, Neural plasticity


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Non-invasive brain stimulation (NIBS) has become a popular tool in neuroscience, as a method to study the brain (e.g. neurophysiology and cognition) or as a treatment for neurological conditions (e.g. mental health disorders). There are a growing range of NIBS techniques that deliver transcranial stimulation (e.g. magnetic, electrical and ultrasound stimulation) which have been shown to be effective in altering neural activity or plasticity in animal models and humans.

Despite the wide use of NIBS in basic and clinical neuroscience, the majority of NIBS protocols, cellular mechanisms and efficacy have been investigated in the young adult brain. Given the clear anatomical and physiological differences that occur in the brain across the lifespan, it is likely that the evidence from young adults cannot be generalized to all ages. Therefore, there is a critical need to characterize and optimize the use of NIBS in younger and older brains to develop more effective stimulation protocols and treatment strategies for these demographics.

We seek submissions that investigate the effect of NIBS in the developing and aged brain from gene expression and single cells (neurons and glia) to neural networks and behavior. Studies using human participants (clinical and pre-clinical populations), animals models as well as theoretical and computational models are encouraged. We welcome manuscripts in any of the accepted article formats (e.g. original articles, data reports, technology report, opinion pieces or mini-reviews).


Keywords: Transcranial magnetic stimulation, Transcranial electrical stimulation, Transcranial ultrasound stimulation, Static magnetic stimulation, Aging, Development, Neural plasticity


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

01 October 2021 Abstract
01 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

01 October 2021 Abstract
01 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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