Cardiovascular disease is the most common cause of mortality worldwide. Impaired cardiovascular metabolic homeostasis is considered as a serious comorbidity of diabetes, hypertension and obesity, which is a high risk factor for stroke, coronary disease, microvascular dysfunction, and heart failure. However, current medicines have limited impacts on the maintenance of cardiovascular metabolism.
Therefore, investigations of underlying mechanisms and clinical interventions on cardiovascular metabolisms are urgently needed. The objects of this research topic include: deciphering physiological regulation pathways involved in cardiovascular metabolism; exploring the molecular basis underlying impaired cardiovascular metabolism in response to pathological stress; developing novel assessments to monitor the alterations of cardiovascular metabolism in the fact of stroke, heart attack and cardiac dysfunction; and providing the novel insights into therapeutic approaches to treat cardiovascular disease.
This research topic is devoted to encompassing preclinical research and clinical studies on cardiovascular metabolism under pathological stress, ranging from the molecular mechanisms to implications of clinical practice.
All original research, review articles, mini reviews, and case reports on the following research themes are welcome: investigating the physio-pathological roles and regulation of cardiovascular lipid and glucose metabolism; providing an advanced understanding of metabolomics in the pathogenesis of cardiovascular disease; identifying novel imaging methods and biomarkers for diagnosing of cardiovascular metabolic disturbance; shedding a light on the potential treatment strategies for cardiovascular disease by maintaining metabolic homeostasis.
Cardiovascular disease is the most common cause of mortality worldwide. Impaired cardiovascular metabolic homeostasis is considered as a serious comorbidity of diabetes, hypertension and obesity, which is a high risk factor for stroke, coronary disease, microvascular dysfunction, and heart failure. However, current medicines have limited impacts on the maintenance of cardiovascular metabolism.
Therefore, investigations of underlying mechanisms and clinical interventions on cardiovascular metabolisms are urgently needed. The objects of this research topic include: deciphering physiological regulation pathways involved in cardiovascular metabolism; exploring the molecular basis underlying impaired cardiovascular metabolism in response to pathological stress; developing novel assessments to monitor the alterations of cardiovascular metabolism in the fact of stroke, heart attack and cardiac dysfunction; and providing the novel insights into therapeutic approaches to treat cardiovascular disease.
This research topic is devoted to encompassing preclinical research and clinical studies on cardiovascular metabolism under pathological stress, ranging from the molecular mechanisms to implications of clinical practice.
All original research, review articles, mini reviews, and case reports on the following research themes are welcome: investigating the physio-pathological roles and regulation of cardiovascular lipid and glucose metabolism; providing an advanced understanding of metabolomics in the pathogenesis of cardiovascular disease; identifying novel imaging methods and biomarkers for diagnosing of cardiovascular metabolic disturbance; shedding a light on the potential treatment strategies for cardiovascular disease by maintaining metabolic homeostasis.