Each year nearly half a million people are diagnosed with new cases of pancreatic cancer, and due to the absence of specific symptoms in the early stages of the disease, most patients commonly aren’t diagnosed until late in disease progression. Pancreatic cancer is also known for having very low survival rates, a 5 year survival rate of less than 5% have been reported since 2011. Nevertheless, even pancreatic cancer therapy is challenging.
Surgical resection still represents the most important therapy for pancreatic cancer, however surgery is limited to roughly 10% of pancreatic cancer patients at the moment of the first detection. Moreover, pancreatic surgery is still burdened with intraoperative risks, higher rates of postoperative morbidity and not negligible mortality, even in high volume centers. Furthermore, postoperative quality of life implications resulting from decreased pancreatic function after surgery need to be considered.
Improving outcomes for pancreatic cancer patients undergoing pancreatic resection can come from refining interventions in presurgical, intraoperative and postsurgical steps of cancer care. Pancreatic cancer behavior is unpredictable, regarding sites of tumor growth, and metastatic spread; these variables mean that a “one size fits all” approach is impossible. Consequently further researches are needed in this field, and the aim of this research topic is to bring together all relevant research in the field to provide pancreatic cancer care teams with new options in treating and caring patients undergoing surgery for this lethal disease, or refinements on existing procedures and pathways of care provided to patients.
We welcome Original Research, leading-edge Reviews and Clinical Trials related, but not limited, to the following aspects:
- Refinements to resection procedures
- Presurgical considerations leading to improved postoperative outcomes
- Postsurgical interventions improving patient outcomes
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
Each year nearly half a million people are diagnosed with new cases of pancreatic cancer, and due to the absence of specific symptoms in the early stages of the disease, most patients commonly aren’t diagnosed until late in disease progression. Pancreatic cancer is also known for having very low survival rates, a 5 year survival rate of less than 5% have been reported since 2011. Nevertheless, even pancreatic cancer therapy is challenging.
Surgical resection still represents the most important therapy for pancreatic cancer, however surgery is limited to roughly 10% of pancreatic cancer patients at the moment of the first detection. Moreover, pancreatic surgery is still burdened with intraoperative risks, higher rates of postoperative morbidity and not negligible mortality, even in high volume centers. Furthermore, postoperative quality of life implications resulting from decreased pancreatic function after surgery need to be considered.
Improving outcomes for pancreatic cancer patients undergoing pancreatic resection can come from refining interventions in presurgical, intraoperative and postsurgical steps of cancer care. Pancreatic cancer behavior is unpredictable, regarding sites of tumor growth, and metastatic spread; these variables mean that a “one size fits all” approach is impossible. Consequently further researches are needed in this field, and the aim of this research topic is to bring together all relevant research in the field to provide pancreatic cancer care teams with new options in treating and caring patients undergoing surgery for this lethal disease, or refinements on existing procedures and pathways of care provided to patients.
We welcome Original Research, leading-edge Reviews and Clinical Trials related, but not limited, to the following aspects:
- Refinements to resection procedures
- Presurgical considerations leading to improved postoperative outcomes
- Postsurgical interventions improving patient outcomes
Important Note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) will not be accepted in any of the sections of Frontiers in Oncology.
