Around 20–25% of the world's adult population has metabolic syndrome (MetSyn), a cluster of metabolic disorders such as insulin resistance, dysglycemia, dyslipidemia, central adiposity with visceral fat accumulation, and hypertension. MetSyn is linked to high risk of type 2 diabetes and cardiovascular disease, thus being an important public health and clinical problem. Due to its impact on host immunity and metabolism, the gut microbiome is a possible culprit in triggering MetSyn. Therefore, manipulation of the gut microbiome (via diet, prebiotics, probiotics, postbiotics, etc) is an essential tool in treating various complications of MetSyn.
Individual clinical trials reported that specific MetSyn symptoms were alleviated after treatment with probiotic foods or supplements containing lactobacilli and bifidobacteria, but the results have been inconclusive. Hence, research is still needed to tackle the role of microbiome manipulation strategies on metabolic disorders management.
The scope of the current Research Topic is to report new findings in the field of microbiome research and MetSyn including microbiota patterns linked to MetSyn, effect of dietary/probiotic/prebiotic/postbiotic interventions on MetSyn complications, host-microbe interations in metabolic disease, clinical trials using microbiota targeting, as well as personalized medicine approaches.
We welcome submissions of original research articles, reviews, systematic reviews, as well as short communications.
Around 20–25% of the world's adult population has metabolic syndrome (MetSyn), a cluster of metabolic disorders such as insulin resistance, dysglycemia, dyslipidemia, central adiposity with visceral fat accumulation, and hypertension. MetSyn is linked to high risk of type 2 diabetes and cardiovascular disease, thus being an important public health and clinical problem. Due to its impact on host immunity and metabolism, the gut microbiome is a possible culprit in triggering MetSyn. Therefore, manipulation of the gut microbiome (via diet, prebiotics, probiotics, postbiotics, etc) is an essential tool in treating various complications of MetSyn.
Individual clinical trials reported that specific MetSyn symptoms were alleviated after treatment with probiotic foods or supplements containing lactobacilli and bifidobacteria, but the results have been inconclusive. Hence, research is still needed to tackle the role of microbiome manipulation strategies on metabolic disorders management.
The scope of the current Research Topic is to report new findings in the field of microbiome research and MetSyn including microbiota patterns linked to MetSyn, effect of dietary/probiotic/prebiotic/postbiotic interventions on MetSyn complications, host-microbe interations in metabolic disease, clinical trials using microbiota targeting, as well as personalized medicine approaches.
We welcome submissions of original research articles, reviews, systematic reviews, as well as short communications.
