Due to the success of the Research Topic
Advances in Understanding and Controlling Bacteria-Material Interactions, with a Focus on how Bacteria Sense a Surface we have launched a volume II. Bacteria can colonize essentially all materials and form multicellular structures, known as biofilms, with bacteria embedding themselves in an extracellular matrix. Due to significantly enhanced resistance to a variety of stresses, bacteria in a biofilm-mode of growth can survive harsher conditions as compared with their planktonic counterparts; and thus are found ubiquitously in both natural and built environments.
Bacteria are known to sense their environment, including pH, nutrient conditions, presence of antimicrobials, neighboring cells, and the chemical and physical properties of substratum materials. For instance, upon adhesion to a surface, bacteria may respond by excretion of extracellular-polymeric-substances (EPS) through a mechanism called mechanosensing, allowing them to grow in their preferred, matrix-protected biofilm-mode of growth. While the “good” biofilms have wide applications, such as in bioremediation and biofuel production, “bad” biofilms are problematic as they are involved in numerous drug resistant infections and biofouling in industrial settings.
Over the past decades, research has focused on controlling the numbers of bacteria adhering to surfaces in order to promote the “good” biofilms and find better solutions to control the “bad” ones. However, it may be equally if not more important to understand how bacteria interact and sense their environment in order to control their adaptive responses to promote or inhibit biofilm formation.
In this collection, we welcome contributions from researchers in this active and emerging field to present new findings (both experimental and computational studies) and reviews of recent advances. The topics of interest include but are not limited to:
(1) Bacterial genes and pathways involved in sensing material properties.
(2) New methods and tools to characterize bacteria-material interactions.
(3) Effects of material properties on bacterial attachment.
(4) New materials or surface design to promote or reduce biofilm formation.
(5) New control agents that can promote or reduce biofilm formation.
(6) Influence of nanostructures and micron scale topographies on bacteria-material interactions.
