The human gut is the home of millions of different bacteria, which together with fungi and viruses constitute what we call the microbiota. The gut microbiota is essential for the correct functioning of our organisms, by modulating the systemic immune response, the immune homeostasis, the production of vitamins, modulation of xenobiotics, and protection against pathogens.
Alteration of the gut microbiota composition is called dysbiosis and is linked to several disorders, gastrointestinal and non, such as inflammatory bowel diseases, autistic spectrum disorders, depression, cardiovascular health, and sepsis.
Fecal microbiota transplantation (FMT) is a technique that helps modulate the gut microbiome toward eubiosis. The procedure has been initially described in the late fifties to treat pseudomembranous colitis and then gained attention in recent years as an efficient tool to alleviate a number of diseases.
Only a part of these disorders and their treatment through fecal microbiota transplantation has been addressed in proper clinical studies, such as obesity, non-alcoholic fatty liver disease, cardiovascular inflammation, and neurological disorders.
With this Research Topic in Frontiers in Medicine, we aim to collect all the recent advances in fecal microbiota transplantation as a therapeutic tool for gastrointestinal and non-gastrointestinal disorders.
The human gut is the home of millions of different bacteria, which together with fungi and viruses constitute what we call the microbiota. The gut microbiota is essential for the correct functioning of our organisms, by modulating the systemic immune response, the immune homeostasis, the production of vitamins, modulation of xenobiotics, and protection against pathogens.
Alteration of the gut microbiota composition is called dysbiosis and is linked to several disorders, gastrointestinal and non, such as inflammatory bowel diseases, autistic spectrum disorders, depression, cardiovascular health, and sepsis.
Fecal microbiota transplantation (FMT) is a technique that helps modulate the gut microbiome toward eubiosis. The procedure has been initially described in the late fifties to treat pseudomembranous colitis and then gained attention in recent years as an efficient tool to alleviate a number of diseases.
Only a part of these disorders and their treatment through fecal microbiota transplantation has been addressed in proper clinical studies, such as obesity, non-alcoholic fatty liver disease, cardiovascular inflammation, and neurological disorders.
With this Research Topic in Frontiers in Medicine, we aim to collect all the recent advances in fecal microbiota transplantation as a therapeutic tool for gastrointestinal and non-gastrointestinal disorders.