About this Research Topic
SARS-CoV-2 enters host cells by first attaching to angiotensin-converting enzyme 2 (ACE2). ACE2 is expressed on tissue throughout the body, in the lungs, kidneys, gastrointestinal tract, and the adrenal and pituitary glands. Evidence suggests this is a possible connection point for Covid-19 to affect the hypothalamic-pituitary-adrenal (HPA) axis along with the expression of numerous pituitary and endocrine disorders. Observations of comorbidities and clinical outcomes such as altered growth hormone levels and disturbance of the HPA axis have been noted in Covid-19 cases around the world, but the exact connection to the disease remains unexplored.
This Research Topic will compile research relating to the relationship between Covid-19 and various aspects of pituitary endocrinology. Research discussing pituitary disorders (E.g., Cushing’s Syndrome and Disease, adrenal insufficiency, acromegaly, etc.), reduced or altered pituitary and adrenal gland functionality, and related topics are particularly encouraged. We welcome original research, review, mini review, systematic review, and perspective manuscripts.
*For articles relating to other aspects of Covid-19 and endocrine research, please see our related Research Topics
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Keywords: covid-19, coronavirus, SARS-CoV-2, pituitary adenoma
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.