In Europe, rare diseases have a prevalence of less than 1 in 2,000 individuals, while in the US a disorder is considered rare if it occurs in less than 200,000 people (according to the Working Group for the Inherited Kidney Diseases of the European Renal Association and European Dialysis and Transplant Association). There are more than 150 different conditions with rare kidney injury, the majority being inherited. In addition to their high economic impact, these diseases affect the quality of life and social integration of the affected children and families, due to the altered physical, cognitive, and psychosocial development. Furthermore, in many of these conditions, we are far from achieving a consensus regarding their management, these patients spending years visiting multiple health care providers before even receiving an accurate diagnosis. However, the therapeutic advances in rare kidney disease prolong patient survival, having promising results on patient outcomes.
In this Research Topic, we welcome original research articles, case reports, and reviews on any of the rare diseases that affect children, such as Alport syndrome, amyloidosis, autosomal dominant/ recessive polycystic kidney disease (ADPKD/ARPKD), cystinosis, Fabry disease, focal segmental glomerulosclerosis (FSGS), Goodpasture's syndrome, hemolytic uremic syndrome (HUS), Henoch-Schönlein purpura, and IgA nephropathy (Berger’s disease).
In Europe, rare diseases have a prevalence of less than 1 in 2,000 individuals, while in the US a disorder is considered rare if it occurs in less than 200,000 people (according to the Working Group for the Inherited Kidney Diseases of the European Renal Association and European Dialysis and Transplant Association). There are more than 150 different conditions with rare kidney injury, the majority being inherited. In addition to their high economic impact, these diseases affect the quality of life and social integration of the affected children and families, due to the altered physical, cognitive, and psychosocial development. Furthermore, in many of these conditions, we are far from achieving a consensus regarding their management, these patients spending years visiting multiple health care providers before even receiving an accurate diagnosis. However, the therapeutic advances in rare kidney disease prolong patient survival, having promising results on patient outcomes.
In this Research Topic, we welcome original research articles, case reports, and reviews on any of the rare diseases that affect children, such as Alport syndrome, amyloidosis, autosomal dominant/ recessive polycystic kidney disease (ADPKD/ARPKD), cystinosis, Fabry disease, focal segmental glomerulosclerosis (FSGS), Goodpasture's syndrome, hemolytic uremic syndrome (HUS), Henoch-Schönlein purpura, and IgA nephropathy (Berger’s disease).
